Results 11 to 20 of about 1,736,990 (170)

The role of SET/I2PP2A in canine mammary tumors

open access: yesScientific Reports, 2017
Canine mammary tumor is the most common neoplasm in female dogs, and it has generated considerable attention as a translational model for human breast cancer.
Satoru Kake   +12 more
doaj   +4 more sources

Doxorubicin as a Potential Treatment Option in Canine Mammary Tumors

open access: yesVeterinary Sciences, 2023
Canine mammary tumors represent one of the leading malignant pathologies in female dogs, displaying the importance of efficient therapeutic findings, besides the golden-standard surgery, able to limit the development of the disease.
Madalina Luciana Gherman   +4 more
doaj   +4 more sources

Dysregulation of PI3K/Akt/PTEN Pathway in Canine Mammary Tumor

open access: yesAnimals, 2021
The PI3K/Akt/PTEN axis is one of the most important signaling pathways in tumorigenesis. Recently, mutation of PIK3CA has been highlighted due to the similarities of mutational hotspots in both dogs and humans.
Soo-Hyeon Kim   +5 more
doaj   +2 more sources

C6 Ceramide Inhibits Canine Mammary Cancer Growth and Metastasis by Targeting EGR3 through JAK1/STAT3 Signaling

open access: yesAnimals
Cancer is the leading cause of death in both humans and companion animals. Canine mammary tumor is an important disease with a high incidence and metastasis rate, and its poor prognosis remains a serious clinical challenge.
Jiayue Liu   +5 more
doaj   +2 more sources

The expression of carbonic anhydrase in canine mammary gland and mammary gland tumor

open access: yesJournal of Veterinary Medical Science, 2014
Carbonic anhydrase (CA), a metallo-enzyme containing zinc, broadly distributes in mammalian tissues and participates in physiological regulation such as respiration, acid-base balance, ion transport, bone resorption, as well as the development of tumor ...
李衛民   +7 more
core   +5 more sources

EXPRESSION OF E- CADHERINE IN CANINE MAMMARY TUMORS [PDF]

open access: yesHorizons - International Scientific Journal, 2020
Reduction of expression of E-cadherin in canine mammary tumors has been correlated with invasive behavior, lymph node metastases and shorter survival period after tumor removal. The aim of this study was to examine the expression of E-cadherin in canine
Nikola Karabolovski   +8 more
doaj   +2 more sources

Enhancing the Anti-Tumor Efficacy of NK Cells on Canine Mammary Tumors through Resveratrol Activation

open access: yesAnimals
In order to explore the therapeutic effect of Resveratrol (Res)-activated Natural Killer (NK) cells on canine mammary tumors, this study employed a range of assays, including wound healing, colony formation, Transwell, flow cytometry, and Western blot ...
Tingting Zhu   +5 more
doaj   +2 more sources

Machine learning determines stemness associated with simple and basal-like canine mammary carcinomas

open access: yesHeliyon
Simple and complex carcinomas are the most common type of malignant Canine Mammary Tumors (CMTs), with simple carcinomas exhibiting aggressive behavior and poorer prognostic.
Pedro L.P. Xavier   +6 more
doaj   +2 more sources

Canine Mammary Tumors [PDF]

open access: yesPathologia veterinaria, 1970
A retrospective study was conducted of 1,366 cases of canine mammary neoplasms derived from 3 different populations of dogs. The mean ages for occurrence of mammary tumors varied between populations studied from the ninth to eleventh years with malignant neoplasms tending to occur later than benign. Irradiation had no effect on incidence.
J E, Moulton   +3 more
openaire   +2 more sources

Amyloid in Canine Mammary Tumors [PDF]

open access: yesVeterinary Pathology, 1985
In canine mammary carcinomas, amyloid was present as amyloid-containing corpora amylacea and as local deposits between neoplastic epithelial cells or in stromal tissue. Histochemical staining methods revealed that this amyloid was not of the AA-type amyloid and contained tryptophan. The possible pathogenesis of this amyloid deposition is discussed.
J H, Vos, E, Gruys
openaire   +2 more sources

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