Results 201 to 210 of about 31,037 (228)
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Chronic pain presents significant personal, psychological, and socioeconomic hurdles, impacting over 30% of adults worldwide and substantially contributing to disability. Unfortunately, current pharmacotherapy often proves inadequate, leaving fewer than 70% of patients with relief.
Nascimento, Glauce Crivelaro +4 more
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Nascimento, Glauce Crivelaro +4 more
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Cannabidiol (CBD) has been investigated for several therapeutic applications, having reached the clinics for the treatment of certain types of epilepsies. This chapter reviews the potential of CBD for the treatment of substance use disorders (SUD). We will present a brief introduction on SUD and current treatments.
Rayssa C, Briânis +2 more
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Rayssa C, Briânis +2 more
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Metabolism of cannabidiol by the rat
European Journal of Drug Metabolism and Pharmacokinetics, 1991Metabolites of CBD excreted into the bile and perfusion fluid were examined in a rat liver perfusion preparation. Metabolites were extracted with ethyl acetate and identified by GC/MS as TMS derivatives. Four mono- and five di-hydroxy metabolites were identified with major sites of metabolic attack being at C-7 and C-4".
E, Samara, M, Bialer, D J, Harvey
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Cannabidiol and cannabinol in man
Experientia, 1973Le cannabidiol administre a dose de 100 mg par os et de 30 mg par injection i.v. fut inactif dans les sujets d'etude. Le cannabinol, a dose orale de 400 mg, le fut aussi. Ces constituants du cannabis ne contribuent donc pas a l'effet pharmacologique.
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Acta Crystallographica Section B Structural Crystallography and Crystal Chemistry, 1977
P. G. Jones +4 more
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P. G. Jones +4 more
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Cannabidiol Inhibits Human Glioma by Induction of Lethal Mitophagy Through Activating TRPV4
Autophagy, 2021Chunhua Hang, Yan Zhou, Ya-Liang Zhang
exaly
Trial of Cannabidiol for Drug-Resistant Seizures in the Dravet Syndrome
New England Journal of Medicine, 2017Helen Cross +2 more
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An Overview on Synthetic and Biological Activities of Cannabidiol (CBD) and Its Derivatives
Bioorganic Chemistry, 2023Bing-You Yang, Lixia Chen
exaly

