Results 231 to 240 of about 59,439 (317)

Unlocking Selenium Chemical Space via a Programmable Synthesis Platform Bearing Cannabinoid Receptor Recognition Motifs. [PDF]

J Am Chem Soc
Iyer MR, Bhattacharjee P, Dutta S, Lobe MMM, Volesky PD, Godlewski G, Puhl HL, Hassan SA.   +7 more
europepmc   +1 more source

Plant‐Derived Melatonin Inhibits Bacterial Virulence via CpxA/R Two‐Component System

Advanced Science, Volume 13, Issue 32, 9 June 2026.
Plant‐derived melatonin is sensed by CpxAE48/T51, which inhibits the phosphorylation cascade transmission from CpxAH240 to CpxRD52, resulting in the inhibition of DNA‐binding capacity of CpxR and subsequent T3SS genes expression in Pst DC3000. ABSTRACT In defending against pathogens, plants deploy diverse secondary metabolites and signaling molecules ...
Jin‐Wei Wei, Wei Liu, Bili Cao, Dan Zhao, Chengqiang Wang, Xin Hou, Tangyuan Ning, Biao Gong   +7 more
wiley   +1 more source

In silico receptor binding and ex vivo nasal epithelial membrane permeation studies of selected phytocannabinoids. [PDF]

J Cannabis Res
Van Niekerk SE, Cloete T, Van der Kooy F, Hamman JH.   +3 more
europepmc   +1 more source

Effect of plant population on crop growth, floral biomass, and cannabinoid yield in field‐grown hemp

Agrosystems, Geosciences &Environment, Volume 9, Issue 2, June 2026.
Abstract Hemp (Cannabis sativa L.) was recently re‐legalized in the United States and cultivated for various purposes, including floral cannabidiol (CBD), grain, and fiber. Due to prohibition of hemp for a century, research supporting production guidelines, including plant density effects on CBD production, remains limited.
Richard J. Roseberg, Jake Hoyman, Govinda Shrestha   +2 more
wiley   +1 more source

Longitudinal neurocognitive trajectories in a large cohort of youth who use cannabis: combining self-report and toxicology. [PDF]

Neuropsychopharmacology
Wade NE, Sullivan RM, Wallace AL, Visontay R, Szpak V, Lisdahl KM, Huestis MA, Gonçalves PD, Byrne H, Mewton L, Jacobus J, Tapert SF.   +11 more
europepmc   +1 more source

Channel Dysfunction as the Basis for Comorbidities in Multiple Sclerosis and Depression

Archiv der Pharmazie, Volume 359, Issue 6, June 2026.
Ion channel remodelling induced by neuroinflammation in multiple sclerosis alters neuronal excitability and immune signalling, creating shared molecular pathways that link multiple sclerosis pathology to depression and reveal novel pharmacological targets.
Nicole Rychlik, Kay Jüngling, Sven G. Meuth, Thomas Budde, Marta Méndez‐Couz   +4 more
wiley   +1 more source

Cannabinoid-Driven Rewiring of GPCR and Ion Channel Signaling in Lung Cancer. [PDF]

Biomedicines
Heriyanto DS, Nurkolis F, Choi J, Park S, Choi M, Tjandrawinata RR, Rani A, Park MN, Kwak MJ, Shim BS, Kim B.   +10 more
europepmc   +1 more source

Low‐dose cannabidiol increases plasma concentrations of amitriptyline: A clinical drug–drug interaction study

British Journal of Clinical Pharmacology, Volume 92, Issue 6, Page 1595-1606, June 2026.
Abstract Aims Cannabidiol (CBD), the main non‐intoxicating compound from the cannabis plant, is regularly used by patients with chronic pain who also take analgesics. CBD has previously been shown to inhibit CYP‐mediated drug metabolism. This study aimed to characterize the potential pharmacokinetic interaction of CBD with amitriptyline and tramadol ...
Andriy A. Gorbenko, Titiaan E. Post, Pamela K. Strugala, Erica S. Klaassen, Linda E. Klumpers, Saco J. de Visser, Cristina Sempio, Jost Klawitter, Jules A. A. C. Heuberger, Geert J. Groeneveld   +9 more
wiley   +1 more source

Chronic simultaneous inducible nitric oxide synthase (iNOS) and peripheral cannabinoid CB₁ receptors blockade ameliorates pulmonary hypertension in monocrotaline-induced rat model. [PDF]

Front Pharmacol
Ryszkiewicz P, Remiszewski P, Pędzińska-Betiuk A, Mińczuk K, Baranowska-Kuczko M, Weresa J, Malinowska B.   +6 more
europepmc   +1 more source