Results 11 to 20 of about 344 (178)
Canadian Journal of Gastroenterology and Hepatology, 2009 Cannabinoid hyperemesis syndrome is characterized by chronic, heavy use of cannabis, recurrent episodes of severe nausea and intractable vomiting, and abdominal pain. Temporary relief of symptoms is achieved by taking a hot bath or shower, and resolution of the problem when cannabis use is stopped.
Stephen Sullivan
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Cancers, 2021 Cannabinoids, active components of the plant Cannabis sativa, had been used for centuries in ancient medicine as therapeutic remedies for a variety of conditions, before becoming stigmatized due to their psychoactive effects [...]
Marco Falasca, Mauro Maccarrone
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Angewandte Chemie, Volume 135, Issue 49, December 4, 2023., 2023 Ein neues mit sichtbarem Licht schaltbares chemisches Gerüst – basierend auf der “privilegierten Struktur” von Benzimidazol – wurde entwickelt: 2‐Benzimidazol Azo‐Arene. Dieses Gerüst wurde für die Entwicklung von selektiven CB2R‐Liganden mit βArr2 funktioneller Selektivität verwendet.
Sophie A. M. Steinmüller +7 more
wiley +1 more source
Neurogastroenterology &Motility, Volume 35, Issue 10, October 2023., 2023 Here we studied radiographically in conscious rats the effects of sepsis induced by lipopolysaccharide (LPS) on gastrointestinal motility, and assessed the accompanying histological damage caused by the endotoxin in different tissues. Gastric emptying was intensely delayed at all doses, but the intestine was affected in a dose‐ and time‐dependent ...
Marta Castro +7 more
wiley +1 more source
Die Zecke und ich: Parasiten‐Wirt‐Interaktionen zwischen Zecken und Menschen
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 20, Issue 6, Page 818-855, June 2022., 2022 Zusammenfassung Zecken, insbesondere Schildzecken (Ixodidae), die zu den bedeutendsten Überträgern gefährlicher Infektionserreger gehören, saugen für längere Zeit an ihren Wirten. Mit dieser Lebensweise haben sich zahlreiche Anpassungen bei Zecken und ihren Wirten entwickelt, deren pharmakologische Bedeutung zunehmend erkannt wird.
Michael P. Schön
wiley +1 more source
Cannabinoids in Pediatrics [PDF]
The Journal of Pediatric Pharmacology and Therapeutics, 2017 Despite its controversial nature, the use of medical marijuana and cannabis-derived medicinal products grows more popular with each passing year. As of November 2016, over 40 states have passed legislation regarding the use of either medical marijuana or cannabidiol products. Many providers have started encountering patients experimenting with cannabis
Christopher T, Campbell +2 more
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Cannabinoids and glaucoma [PDF]
British Journal of Ophthalmology, 2004 Glaucoma is one of the leading causes of blindness in the world. In spite of the diverse therapeutic possibilities, new and better treatments for glaucoma are highly desirable. Cannabinoids effectively lower the intraocular pressure (IOP) and have neuroprotective actions. Thus, they could potentially be useful in the treatment of glaucoma.
Azuara-Blanco, A. +2 more
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Cannabinoids and Epilepsy [PDF]
Neurotherapeutics, 2015 Cannabis has been used for centuries to treat seizures. Recent anecdotal reports, accumulating animal model data, and mechanistic insights have raised interest in cannabis-based antiepileptic therapies. In this study, we review current understanding of the endocannabinoid system, characterize the pro- and anticonvulsive effects of cannabinoids [e.g ...
Evan C, Rosenberg +3 more
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Heteroadamantyl Cannabinoids [PDF]
Journal of Medicinal Chemistry, 2010 The aliphatic side chain plays a pivotal role in determining the cannabinergic potency of tricyclic classical cannabinoids. We have synthesized a series of analogues in which the C3 position is substituted either directly or through a one-carbon atom linker with an adamantylamine or with an oxa- or an oxazaadamantane. The oxaadamantane pharmacophore in
Darryl D, Dixon +8 more
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Developmental Medicine &Child Neurology, Volume 62, Issue 9, Page 1031-1039, September 2020., 2020 Aim To assess the efficacy, safety, and tolerability of oromucosal nabiximols cannabinoid medicine as adjunct therapy for children with spasticity due to cerebral palsy/traumatic central nervous system injury with inadequate response to existing treatment.
Charlie Fairhurst +4 more
wiley +1 more source