Results 121 to 130 of about 122,153 (397)

Rapid Identification of New Psychoactive Substances in Letters by LA‐APCI‐MS

open access: yesDrug Testing and Analysis, EarlyView.
Laser ablation coupled to molecular mass spectrometry utilizing a modified atmospheric pressure chemical ionization source was used for the detection of synthetic cannabinoid receptor agonists in infused prison mail samples. ABSTRACT New psychoactive substances (NPS), especially synthetic cannabinoid receptor agonists (SCRA), are increasingly smuggled ...
Mark Wesner   +4 more
wiley   +1 more source

Interaction between Cannabinoid System and Toll-Like Receptors Controls Inflammation [PDF]

open access: yes, 2016
Since the discovery of the endocannabinoid system consisting of cannabinoid receptors, endogenous ligands, and biosynthetic and metabolizing enzymes, interest has been renewed in investigating the promise of cannabinoids as therapeutic agents.
McCoy, Kathleen L.
core   +4 more sources

Cannabinoids in Pediatrics [PDF]

open access: yesThe Journal of Pediatric Pharmacology and Therapeutics, 2017
Despite its controversial nature, the use of medical marijuana and cannabis-derived medicinal products grows more popular with each passing year. As of November 2016, over 40 states have passed legislation regarding the use of either medical marijuana or cannabidiol products. Many providers have started encountering patients experimenting with cannabis
Christopher T, Campbell   +2 more
openaire   +2 more sources

Uncovering the molecular targets of phytocannabinoids: mechanistic insights from inverse molecular docking fingerprint approaches

open access: yesFrontiers in Pharmacology
IntroductionAmong diverse chemical profile of Cannabis sativa L., over 100 phytocannabinoids have been identified. The major cannabinoids Δ-9-THC and CBD are well-studied, with approved palliative and therapeutic applications such as appetite stimulation,
Vid Ravnik   +9 more
doaj   +1 more source

The use of cannabinoids in animals and therapeutic implications for veterinary medicine: a review

open access: yesVeterinární Medicína, 2016
Cannabinoids/medical marijuana and their possible therapeutic use have received increased attention in human medicine during the last years. This increased attention is also an issue for veterinarians because particularly companion animal owners now show
L. Landa, A. Sulcova, P. Gbelec
doaj   +1 more source

Cannabinoids as a Potential Alternative to Opioids in the Management of Various Pain Subtypes: Benefits, Limitations, and Risks

open access: yesPain and Therapy, 2023
Introduction Pain is a global phenomenon encompassing many subtypes that include neuropathic, musculoskeletal, acute postoperative, cancer, and geriatric pain.
Samuel P. Ang   +8 more
doaj   +1 more source

Simulation of the Metabolism of New Psychoactive Substances Using Electrochemistry‐Mass Spectrometry: Introducing an Innovative Software Tool for Rapid Data Evaluation

open access: yesDrug Testing and Analysis, EarlyView.
A novel software tool for the rapid and efficient simulation of the metabolism of new psychoactive substances was developed and applied to mimic the metabolism of the synthetic cannabinoid receptor agonist MDMB‐4en‐PINACA. ABSTRACT An innovative software tool for the rapid and efficient simulation of the metabolism of new psychoactive substances (NPS ...
Mark Wesner   +3 more
wiley   +1 more source

An index of fatal toxicity for new psychoactive substances [PDF]

open access: yes, 2018
The final, definitive version of this paper has been published in Journal of Psychopharmacology, February 2018, published by SAGE Publishing, All rights reserved.An index of fatal toxicity for new psychoactive substances has been developed based solely ...
Corkery, John, King, L.A.
core   +2 more sources

The endocannabinoid system regulates both ependymoglial and neuronal cell responses to a tail amputation in the axolotl

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background The endocannabinoid system is a neuromodulatory system implicated in cellular processes during both development and regeneration. The Mexican axolotl, one of only a few vertebrates capable of central nervous system regeneration, was used to examine the role of the endocannabinoid system in the regeneration of the tail and spinal ...
Michael Tolentino   +3 more
wiley   +1 more source

HIV Transgenic Rats Demonstrate Impaired Sensorimotor Gating But Are Insensitive to Cannabinoid (Δ9-Tetrahydrocannabinol)-Induced Deficits [PDF]

open access: gold, 2021
Benjamin Z. Roberts   +7 more
openalex   +1 more source

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