Results 261 to 270 of about 50,545 (304)
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Cannabinoids, cannabinoid receptors and tinnitus
Hearing Research, 2016One hypothesis suggests that tinnitus is a form of sensory epilepsy, arising partly from neuronal hyperactivity in auditory regions of the brain such as the cochlear nucleus and inferior colliculus. Although there is currently no effective drug treatment for tinnitus, anti-epileptic drugs are used in some cases as a potential treatment option. There is
Paul F, Smith, Yiwen, Zheng
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Life Sciences, 2006
After their discovery, the two known cannabinoid receptors, CB(1) and CB(2), have been the focus of research into the cellular signalling mechanisms of cannabinoids. The initial assessment, mainly derived from expression studies, was that cannabinoids, via G(i/o) proteins, negatively modulate cyclic AMP levels, and activate inward rectifying K ...
Dirk G, Demuth, Areles, Molleman
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After their discovery, the two known cannabinoid receptors, CB(1) and CB(2), have been the focus of research into the cellular signalling mechanisms of cannabinoids. The initial assessment, mainly derived from expression studies, was that cannabinoids, via G(i/o) proteins, negatively modulate cyclic AMP levels, and activate inward rectifying K ...
Dirk G, Demuth, Areles, Molleman
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Current Drug Target -CNS & Neurological Disorders, 2005
Since the discovery of an endogenous cannabinoid system, research into the pharmacology and therapeutic potential of cannabinoids has steadily increased. Two subtypes of G-protein coupled cannabinoid receptors, CB(1) and CB(1), have been cloned and several putative endogenous ligands (endocannabinoids) have been detected during the past 15 years.
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Since the discovery of an endogenous cannabinoid system, research into the pharmacology and therapeutic potential of cannabinoids has steadily increased. Two subtypes of G-protein coupled cannabinoid receptors, CB(1) and CB(1), have been cloned and several putative endogenous ligands (endocannabinoids) have been detected during the past 15 years.
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Pharmacology & Therapeutics, 2002
During the last decade, rigorous scientific methods have been applied to determine the effects of cannabinoids on nociceptive neurotransmission. Cannabinoids have been observed to markedly decrease signalling in specific neural pathways that transmit messages about pain.
J Michael, Walker, Susan M, Huang
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During the last decade, rigorous scientific methods have been applied to determine the effects of cannabinoids on nociceptive neurotransmission. Cannabinoids have been observed to markedly decrease signalling in specific neural pathways that transmit messages about pain.
J Michael, Walker, Susan M, Huang
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The American Journal of the Medical Sciences, 2015
Synthetic cannabinoids (SCBs), also known under the brand names of "Spice," "K2," "herbal incense," "Cloud 9," "Mojo" and many others, are becoming a large public health concern due not only to their increasing use but also to their unpredictable toxicity and abuse potential.
Brooke, Mills +2 more
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Synthetic cannabinoids (SCBs), also known under the brand names of "Spice," "K2," "herbal incense," "Cloud 9," "Mojo" and many others, are becoming a large public health concern due not only to their increasing use but also to their unpredictable toxicity and abuse potential.
Brooke, Mills +2 more
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Focus on cannabinoids and synthetic cannabinoids
Clinical Pharmacology & Therapeutics, 2016The recent emergence of a multitude of synthetic cannabinoids (SCs) has generated a wealth of new information, suggesting the usefulness of state‐of‐the‐art on lato sensu cannabinoids. By modulating a plurality of neurotransmission pathways, the endocannabinoid system is involved in many physiological processes that are increasingly explored.
R, Le Boisselier +3 more
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Journal of Ethnopharmacology, 1986
The pharmacology of the cannabinoids is characterized by at least two very provocative phenomena. First, the multiplicity of effects. As I have mentioned throughout this review, most of these effects are due to actions on the central nervous system. The major problem in the search for a therapeutic agent in this series has been due to the inability to ...
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The pharmacology of the cannabinoids is characterized by at least two very provocative phenomena. First, the multiplicity of effects. As I have mentioned throughout this review, most of these effects are due to actions on the central nervous system. The major problem in the search for a therapeutic agent in this series has been due to the inability to ...
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Onkologische Welt, 2018
Im März 2017 wurde in Deutschland per Gesetz die medizinische Anwendung von Cannabispräparaten auf einen Schlag und ohne Indikationsbindung freigegeben. Die Niederlande, das Land, das mit medizinischem Cannabis weltweit die meisten Erfahrungen hat, ist unterdessen am Zurückrudern.
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Im März 2017 wurde in Deutschland per Gesetz die medizinische Anwendung von Cannabispräparaten auf einen Schlag und ohne Indikationsbindung freigegeben. Die Niederlande, das Land, das mit medizinischem Cannabis weltweit die meisten Erfahrungen hat, ist unterdessen am Zurückrudern.
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Catalytic asymmetric synthesis of cannabinoids and menthol from neral
Nature, 2023Hui Zhou +2 more
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