Results 261 to 270 of about 278,963 (360)

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

Correction: Cannabis-based extract for managing pain in dogs with osteoarthritis: efficacy and safety assessment

Frontiers in Pharmacology
Neide Maria Griebeler, Ricardo Penayo Cremonese, Yasmin Rafaela Fakih Correa, Priscila Romero Mazzini Pereira, Amanda Furjan Rial, Emanuela Leite, Maria Victoria Luz Gonçalves, Luiz Renato Marques das Almas, Nedice Borges Cardoso, Fernando Cezar-dos-Santos, Aline Theodoro Toci, Andrés Mojoli Le-Quesne, Francisney Pinto Nascimento   +12 more
doaj   +1 more source

Clinical pain intensity is associated with greater cannabis demand among people who regularly use cannabis. [PDF]

Pain Rep
Bush NJ, Ferguson E, Funez-Ponce M, Yurasek A, Boissoneault J.   +4 more
europepmc   +1 more source

Cannabigerol reverses mechanical allodynia through α2A‐adrenergic modulation of thalamocortical signaling in chemotherapy‐induced neuropathy

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Chemotherapy‐induced peripheral neuropathy (CIPN) is a prevalent and treatment‐resistant side effect of platinum‐based chemotherapy, characterised by mechanical allodynia. Cannabigerol (CBG), a non‐psychoactive cannabinoid, has shown antinociceptive potential, but its site and mechanism of action remain unclear.
Quinn W. Wade, Nathan Morris, Diana E. Sepulveda, Alonso Cortez‐Resendiz, Christopher Brandl, Jennifer E. Lausch, Mariya Starostina, Nicholas M. Graziane   +7 more
wiley   +1 more source

Controlled Use of Cannabis Among Young Adults in Los Angeles Across Changes in Cannabis Policies. [PDF]

Int J Ment Health Addict
Lankenau SE, Ataiants J, Prince M, Fedorova E, Conn BM, Ansell E, Wong CF.   +6 more
europepmc   +1 more source

Evaluation of preclinical antipsychotic models used to support first‐in‐human clinical trials

British Journal of Pharmacology, EarlyView.
Abstract Schizophrenia is regarded as a complex and heterogeneous psychiatric disorder, characterised by diverse symptoms and comorbidities, which complicate both clinical management and drug development. Current pharmacological treatment, primarily based on dopamine D2 receptor antagonism or partial agonism, which has not markedly progressed since the
Thi Viet Ha Nguyen, Declan P. McKernan, John P. Kelly   +2 more
wiley   +1 more source

Comprehensive analysis of the chloroplast genome in Cannabis sativa L. reveals variations in simple sequence repeats among cultivars. [PDF]

Sci Rep
Khabbazi SD.
europepmc   +1 more source

DA SEMENTE AO PRODUTO: GESTÃO POR PROCESSOS, QUALIDADE E RASTREABILIDADE NA ASSOCIAÇÃO BRASILEIRA DE CANNABIS MEDICINAL BCY

Paulo Jordão de Oliveira Cerqueira Fortes, Jamila Ferreira Rocha, Nélson Leal Alencar, Lívio César Cunha Nunes, M. Amaral, Salomon Tinman   +5 more
openalex   +2 more sources

Maternal anorexia nervosa and risk of mental and neurodevelopmental morbidity in offspring

Child and Adolescent Mental Health, EarlyView.
Background Anorexia nervosa has the potential to affect fetal neurodevelopment. We examined the association between maternal anorexia nervosa and mental, substance‐related, and neurodevelopmental morbidity in offspring. Methods We conducted a retrospective cohort study of 1,269,370 children in Quebec, Canada, between 2006 and 2022.
Sam Amar, Gabriel Côté‐Corriveau, Mimi Israël, Howard Steiger, Nancy Low, Nicholas Chadi, Émilie Brousseau, Nahantara Lafleur, Nathalie Auger   +8 more
wiley   +1 more source

Cannabis products and trends in a cohort of young adults: The VapeScan longitudinal study. [PDF]

Tob Induc Dis
McGraw KE, Oelsner EC, LoIacono NJ, Gao S, Anderson W, Sangapalaarachchi D, Illievski V, Liu J, Martins S, Sanchez TR, Shimbo D, Navas-Acien A.   +11 more
europepmc   +1 more source