Results 281 to 290 of about 278,963 (360)
Neuronal hyperexcitability: A key to unraveling hippocampal synaptic dysfunction in Lafora disease
Abstract Background and Objective Lafora disease (LD) is a rare progressive disorder caused by mutations in the EPM2A or EPM2B genes, characterized by the accumulation of Lafora bodies, drug‐resistant epilepsy, and cognitive decline. To investigate the early molecular mechanisms of LD, we studied electrophysiological changes in the dentate gyrus (DG ...
Cinzia Costa +17 more
wiley +1 more source
Prevalence and correlates of substance use among middle and high school students in Settat Province, Morocco. [PDF]
El Moubchiri C +3 more
europepmc +1 more source
Is There an Industry Effect of SPAC Merger Announcements?
ABSTRACT This study investigates whether SPAC merger announcements affect the target firms' industry rivals. Using a sample of 468 SPAC mergers from 2016 to 2023, the results indicate that rival firms experience significant negative abnormal returns, especially around smaller and riskier deals that yield lower announcement returns for SPACs. Additional
Carene Boucher
wiley +1 more source
Abstract Objective To assess the prevalence, frequency, and characteristics of headache disorders in transgender individuals receiving gender‐affirming hormone therapy (GAHT), and to explore the relationship between GAHT and headache pathophysiology.
Lucia Jimena Zavala +4 more
wiley +1 more source
Proceedings of the 2025 Cannabis Clinical Outcomes Research Conference. [PDF]
Goodin AJ +6 more
europepmc +1 more source
Abstract Objective/Background This study was undertaken to assess participants' impression of use and satisfaction with STS101 in a long‐term, open‐label safety study. The ASCEND study assessed the safety and tolerability of STS101, an investigational drug–device combination of 5.2 mg dihydroergotamine in a single‐use nasal delivery device for the ...
Jessica Ailani +4 more
wiley +1 more source
Problematic social media use among recreational cannabis users in Québec: A Cross-Sectional study. [PDF]
Deli-Houssein R +7 more
europepmc +1 more source
Abstract Objective To assess the efficacy of cannabis for the treatment of acute migraine. Background Preclinical and retrospective studies suggest cannabinoids may be effective in migraine treatment. However, there have been no randomized clinical trials examining the efficacy of cannabinoids for acute migraine.
Nathaniel M. Schuster +6 more
wiley +1 more source
Neurocognitive outcomes in adolescents with and without four weeks of cannabis abstinence: a randomized clinical trial using contingency management. [PDF]
Schuster RM +5 more
europepmc +1 more source

