Results 31 to 40 of about 10,444 (254)

Translational hurdles with cannabis medicines [PDF]

Pharmacoepidemiology and Drug Safety, 2020
AbstractPurposeInternationally, there has been widespread medical use of cannabis medicines before rigorous evaluations in randomised controlled trials (RCTs). Some advocates of medicinal use of cannabis argue that real‐world evidence (RWE) can be a substitute for or at least supplement evidence from RCTs. We explore the utility, limitations and impact
Myfanwy Graham, Catherine J. Lucas, Jennifer Schneider, Jennifer H. Martin, Wayne Hall   +4 more
openaire   +5 more sources

Multivariate Robustness Modeling of Cannabidiol and Δ⁹-Tetrahydrocannabinol Quantification Using Two-Level Full Factorial Design

Scientia Pharmaceutica
The present study aimed to establish a robustness modeling framework for the determination of cannabidiol (CBD) and Δ9-tetrahydrocannabinol (THC) in cannabis extract using a multivariate approach.
Athip Maha, Thanapat Songsak, Surang Leelawat, Chaowalit Monton   +3 more
doaj   +1 more source

Clinical Evidence of Magistral Preparations Based on Medicinal Cannabis

Pharmaceuticals, 2021
Cannabis has been widely used as a medicinal plant for millennia; however, studies related to its main components were first conducted in 1960. Subsequently, laboratories have produced new components and structures related to its active biological ...
Sara Arias, Marta Leon, Diego Jaimes, Rosa-Helena Bustos   +3 more
doaj   +1 more source

Cannabinoides y su uso terapéutico

Gaceta Médica de México, 2023
El cannabis se ha utilizado con fines medicinales durante muchos años; su prohibición a mediados del siglo XX ha detenido la investigación relativa a su utilidad terapéutica. En años recientes se ha intensificado el debate sobre el empleo de cannabis con
Sergio Islas-Andrade, Luisa L. Rocha-Arrieta, Oscar Arrieta, Miguel A. Celis, Judith Domínguez-Cherit, Alberto Lifshitz, Armando Mansilla-Olivares, Iris Martínez, Alberto J. Mimenza-Alvarado, Mucio Moreno, Alejandro A. Reyes-Sánchez, Guillermo J. Ruiz-Argüelles, Antonio Soda-Merhy, Julio Sotelo, Sonia Toussaint, Diana Vilar-Compte, Emma Verástegui   +16 more
doaj   +1 more source

Cannabis medicinal

Salud Colectiva, 2022
La salud es un derecho humano. Para garantizar ese derecho, resulta esencial que las actividades destinadas a la salud en diferentes niveles, clínica, investigación o docencia contribuyan a generar un sistema eficiente, de excelencia, equitativo, justo y solidario. Desde esta perspectiva, abordamos las opciones del uso del cannabis medicinal.
openaire   +3 more sources

Conflicting forces in the implementation of medicinal cannabis regulation in Uruguay

Journal of Cannabis Research, 2023
Background Uruguay is widely known as a pioneer country regarding cannabis regulation policies, as it was the first state to regulate the cannabis market for both recreational and medicinal purposes in 2013.
Eliana Alvarez, Rosario Queirolo, Belen Sotto   +2 more
doaj   +1 more source

Online survey of medicinal cannabis users: Qualitative analysis of patient-level data

Frontiers in Pharmacology, 2022
Aim: To characterize perceived benefits and challenges experienced by medicinal cannabis users.Methods: An anonymous online survey collected demographics, health information, and open-ended responses from medicinal cannabis users regarding perceptions ...
Albert Garcia-Romeu, Joshua Elmore, Rhiannon E. Mayhugh, Nicolas J. Schlienz, Erin L. Martin, Justin C. Strickland, Marcel Bonn-Miller, Heather Jackson, Ryan Vandrey   +8 more
doaj   +1 more source

Motherhood and medicinal cannabis

Drug and Alcohol Review
AbstractIntroductionWomen are emerging as a key demographic for medicinal cannabis (MC) use in countries that have implemented MC reforms. However, research on mothers' experiences of consuming MC remains limited beyond studies on perinatal outcomes.
Vinuli Withanarachchie, Marta Rychert, Chris Wilkins   +2 more
openaire   +2 more sources

Tandem Duplication‐Driven Neofunctionalization of UDP‐Glycosyltransferases Shapes the Diversification of Triterpenoid Saponins in the Cucurbitaceae

Advanced Science, EarlyView.
We present a chromosome‐level genome assembly of Siraitia grosvenorii and, through comparative genomics, uncover a conserved UGT73 tandem array driving triterpenoid saponin diversification in Cucurbitaceae. Crystalized SgUGT73AM30 further reveals the regioselectivity mechanism underlying its catalytic activity.
Guangyi Wang, Mengmeng Li, Xuehui Dai, Yanchen Zhang, Yuhan Wu, Zhaotao Yan, Chenfei Tian, Hongkai Fan, Haili Liu, Xiaowei Zhang, Yiming Yang, Jiayu Lu, Yuwei Sun, Yong Wang   +13 more
wiley   +1 more source

Acute toxicity of ADB‐CHMINACA ‐ a case series of patients with pronounced central nervous symptoms including the posterior reversible encephalopathic syndrome

British Journal of Clinical Pharmacology, EarlyView.
Aim This report presents a series of 16 patients who were admitted to the emergency department following confirmed intake of the potent synthetic cannabinoid ADB‐CHMINACA. Methods The cases are drawn from a prospective observational study following the recreational use of synthetic cannabinoids.
Maren Hermanns‐Clausen, Michaela Sommer, Annette Zschiesche, Verena Angerer, Martin Scheu, Florian Eyer, Johannes Nadler, Volker Auwärter   +7 more
wiley   +1 more source