Results 61 to 70 of about 40,165 (234)

Development of a novel risk score reflecting the relative harm potential of synthetic cannabinoids based on prevalence estimates, well‐documented intoxication cases and basic pharmacological data

Addiction, EarlyView.
Abstract Background and aims While the health hazards of synthetic cannabinoid receptor agonists (SCRAs) are often approximated using in vitro pharmacological parameters as surrogate, this approach fails to consider pharmacokinetic and pharmacodynamic complexity.
Michaela J. Sommer, Katharina Elisabeth Grafinger, Maren Hermanns‐Clausen, Volker Auwärter   +3 more
wiley   +1 more source

Análise da utilização da Cannabis sativa na prática da clínica veterinária de pequenos animais: uma visão atual

Pubvet
No cenário atual, a Cannabis sativa tem tido um importante destaque devido ao crescente uso de seus componentes na terapêutica de diversas patologias, tanto na medicina humana como na medicina veterinária.
Hellen Thawane Duarte, Luciana de Souza
doaj   +1 more source

Thaumatin‐Like Proteins in Molecular Allergy Diagnostics: Uncommon, Co‐Sensitized, and Clinically Inconspicuous? Insights From an Italian Cohort

Allergy, EarlyView.
This study assessed the prevalence, quantitative IgE levels, co‐sensitization patterns, and clinical significance of IgE reactivity to two TLPs—Act d 2 (kiwi) and Mal d 2 (apple)—in a large Italian allergic cohort. Thaumatin‐like protein (TLP) sensitization was uncommon (1.9%) and usually clinically silent when isolated.
Enrico Scala, Damiano Abeni, Mauro Giani, Valeria Villella, Elisabetta Caprini, Ignazio Brusca, Lorenzo Cecchi, Danilo Villalta, Riccardo Asero   +8 more
wiley   +1 more source

High resolution melting curve analysis revealed SNPs in major cannabinoid genes associated with drug and non-drug types of cannabis

Biotechnology & Biotechnological Equipment, 2017
Cannabis sativa L. has a long history of cultivation as food, fibre, medicine and recreational drugs. Production of high tetrahydrocannabinol (THC) plants for narcotic use (drug type) is illegal and under control in most countries.
Tahereh Borna, Seyed Alireza Salami, Majid Shokrpour   +2 more
doaj   +1 more source

Phytocannabinoids as novel therapeutic agents in CNS disorders [PDF]

, 2012
The Cannabis sativa herb contains over 100 phytocannabinoid (pCB) compounds and has been used for thousands of years for both recreational and medicinal purposes.
Hill, Andrew J., Stephens, Gary J., Whalley, Benjamin J., Williams, Claire M.   +3 more
core   +1 more source

New Allergens Approved by the WHO/IUIS Allergen Nomenclature Sub‐Committee in 2021–2024 and Their Significance for Future Diagnostics, Regulation, and Research. An EAACI Task Force Report

Allergy, EarlyView.
ABSTRACT The WHO/IUIS Allergen Nomenclature Sub‐Committee is an international body of experts that maintains the systematic nomenclature of allergenic proteins by assigning official names to newly identified allergens submitted by researchers. Here, we summarize the data on new allergens approved between 2021 and 2024.
Christian Radauer, Gabriele Gadermaier, Richard E. Goodman, Alain Jacquet, Uta Jappe, Andreas L. Lopata, Anna Pomés, Monika Raulf, Keity S. Santos, Josefina Zakzuk, Yuzhu Zhang, Joana Vitte, on behalf of the WHO/IUIS Allergen Nomenclature Sub‐Committee   +12 more
wiley   +1 more source

Effect of hydroalcoholic extract of Cannabis sativa on cell survival and differentiation of mesenchymal stem cells derived from human adipose tissue to osteoblast-like cells

مجله دانشگاه علوم پزشکی گرگان, 2019
Background and Objective: The resin secretions of Cannabis sativa are called Hashish, which has medicinal and psychological properties. The most important psychoactive compound of this plant is THC (Delta-9-Tetrahydrocannabinol), which can stimulate ...
Mehregan Jamshidi, Seyed Ebrahim Hosseini, Davood Mehrabani, Masoud Amini   +3 more
doaj  

Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?

British Journal of Pharmacology, EarlyView.
Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli, Emanuela Micioni Di Bonaventura, Giacomo Einaudi, Gustavo Provensi, Alessia Costa, Claudio D'Addario, Carlo Cifani, Maria Vittoria Micioni Di Bonaventura   +7 more
wiley   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

An examination into the possibility of the UK being a predominantly cannabis producing nation and a methodology of cultivation techniques [PDF]

, 2016
Previously, the UK has been known to heavily import cannabis from producer countries, more recently vast quantities of cannabis farms are being discovered throughout the nation.
O'Hagan, A, Parker, A
core