Results 111 to 120 of about 124,142 (278)
BioMed Research International, 2018 In the last decades, a lot of attention has been paid to the compounds present in medicinal Cannabis sativa L., such as Δ9-tetrahydrocannabinol (Δ9-THC) and cannabidiol (CBD), and their effects on inflammation and cancer-related pain. The National Cancer
Federica Pellati +5 more
semanticscholar +1 more source
Molecules, 2020 Industrial hemp (Cannabis sativa L. Family Cannabaceae) contains a vast number of bioactive relevant compounds, namely polyphenols including flavonoids, phenolic acids, phenol amides, and lignanamides, well known for their therapeutic properties ...
L. Izzo +6 more
semanticscholar +1 more source
Novel approaches for drug development against chronic primary pain: A systematic review
British Journal of Pharmacology, EarlyView.Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus +5 more
wiley +1 more source
, 2010 The use of cannabis is embedded within many societies, mostly used by the young and widely perceived to be safe. Increasing concern regarding the potential for cannabis to cause mental health effects has dominated cannabis research and the potential ...
Macleod, J, Reid, P T, Robertson, Roy
core +1 more source
British Journal of Pharmacology, EarlyView.Cardiac remodelling and fibrosis after myocardial infarction or during chronic diseases, such as arterial and pulmonary hypertension or diabetes mellitus, continue to be the more important prognostic factors in determining survival, and so the search for effective anti‐fibrotic interventions is an important target for research and therapy in cardiology.
Anna Krzyżewska +2 more
wiley +1 more source
Effect of cannabis smoking on lung function and respiratory symptoms: a structured literature review [PDF]
, 2016 As cannabis use increases, physicians need to be familiar with the effects of both cannabis and tobacco on the lungs. However, there have been very few long-term studies of cannabis smoking, mostly due to legality issues and the confounding effects of ...
Ind, PW, Ribeiro, LI
core +1 more source
Epilepsia, EarlyView.Abstract Objective This randomized, double‐blind, phase 1b/2a clinical trial was designed to evaluate the safety, tolerability, and efficacy of oral bexicaserin versus placebo for the treatment of seizures in adolescents and adults with developmental and epileptic encephalopathies (DEEs).
Dennis J. Dlugos +74 more
wiley +1 more source
Neuronal hyperexcitability: A key to unraveling hippocampal synaptic dysfunction in Lafora disease
Epilepsia, EarlyView.Abstract Background and Objective Lafora disease (LD) is a rare progressive disorder caused by mutations in the EPM2A or EPM2B genes, characterized by the accumulation of Lafora bodies, drug‐resistant epilepsy, and cognitive decline. To investigate the early molecular mechanisms of LD, we studied electrophysiological changes in the dentate gyrus (DG ...
Cinzia Costa +17 more
wiley +1 more source
Новые технологииIn recent decades interest in hemp seed concentrates, which are characterized by a valuable amino acid composition and high nutritional value, has increased.
A. V. Petrenko +4 more
doaj +1 more source
The alimentary impact of the hemp seed [PDF]
, 2013 Hemp seed and hemp seed oil can supply us with many important substances. Their essential fatty acid compositions are favourable, but they may contain non-psychotropic cannabinoids. Emerging data show that these components can influence the health status
A. Böszörményi +26 more
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