Results 111 to 120 of about 11,029 (284)

Potential Risk of Botulinum Neurotoxin -producing Clostridia Occurrence in Canned Fish. [PDF]

open access: yesJ Vet Res, 2022
Jarosz A   +4 more
europepmc   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Exposure assessment of As, Cd, Hg, and Pb in fish and canned fish collected from local markets at Ramallah city using high-resolution inductively coupled plasma mass spectrometry

open access: yesFrontiers in Sustainable Food Systems
IntroductionFish consumption can be a primary pathway for human exposure to toxic metals such as, Cd, As, Hg, and Pb. Even at relatively low concentrations, long-term exposure to these metals might result in accumulation levels leading to toxicity ...
Baraa Gazzawi   +5 more
doaj   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Factors Affecting Consumer Choice of Canned Fish in Taiwan [PDF]

open access: yes
Survey data on the choice of canned fish were analyzed through stepwise logistic regression. Those who lived in northern Taiwan, those who paid more attention to food taste, those who preferred to eat fish, those who liked to eat sour food, those who ...
Houston, Jack E.   +3 more
core   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Determination of mercury in canned fish / Nurr Maria Ulfa Seruji [PDF]

open access: yes, 2008
Mercury is a harmful heavy metal that bioaccumulates in human body and cause disturbance in human systems. The process biomagnifications that occur in the food chain brings mercury closer to human body since human are at the top levels of the aquatic ...
Seruji, Nurr Maria Ulfa
core  

Influence of Cuttlefish-Ink Extract on Canned Golden Seabream (Sparus aurata) Quality

open access: yesFoods
Four different concentrations of an aqueous extract of cuttlefish (Sepia spp.) ink (CI) were introduced, respectively, into the packing medium employed during golden seabream (Sparus aurata) canning.
Beatriz Martínez   +3 more
doaj   +1 more source

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