Results 101 to 110 of about 677,568 (372)

The mismatch between job openings and job seekers [PDF]

open access: yes
Today's high unemployment rate is often linked to a structural imbalance—a mismatch between the skills and location required to fill vacant jobs and the skills and geographical preferences of the unemployed.
Maria E. Canon, Mingyu Chen
core  

TRPM8 levels determine tumor vulnerability to channel agonists

open access: yesMolecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo   +18 more
wiley   +1 more source

Loss of primary cilia promotes EphA2‐mediated endothelial‐to‐mesenchymal transition in the ovarian tumor microenvironment

open access: yesMolecular Oncology, EarlyView.
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho   +11 more
wiley   +1 more source

Striga Management through Herbicide Resistance: A Public-Private Partnership in Action [PDF]

open access: yes
Striga is an indigenous parasitic weed that attacks cereals and other crops in Africa. In maize croplands alone, Striga infests over 2.3 million ha resulting in 1.6 million tons of grain loss worth US $383 million annually.
Savala, Canon N., Woomer, Paul L.
core   +1 more source

Greater Boston Youth Symphony Orchestras Winter Concert, January 27, 1991 [PDF]

open access: yes, 1991
This is the concert program of the Greater Boston Youth Symphony Winter Concert performance on Sunday, January 27, 1991 at 4:00 p.m., at the Boston University Concert Hall, 855 Commonwealth Avenue, Boston, Massachusetts.
School of Music, Boston University
core  

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner   +6 more
wiley   +1 more source

A DIA‐MS‐based proteomics approach to find potential serum prognostic biomarkers in glioblastoma patients

open access: yesMolecular Oncology, EarlyView.
A DIA‐MS‐based proteomics analysis of serum samples from GB patients and healthy controls showed that high levels of IL1R2 and low levels of CRTAC1 and HRG in serum are associated with poor survival outcomes for GB patients. These circulating proteins could serve as biomarkers for the prediction of outcome in patients with GB.
Anne Clavreul   +11 more
wiley   +1 more source

La lectura literaria ante nuevos retos: canon y mediación en la trayectoria lectora de futuros profesores.

open access: yes, 2014
Based on an analysis of more than sixty reports on own path reading students teachers of pre-school and primary education second during the courses 2011/12 and 2012/13, we have appreciated some relationships relevant between forms of mediation, canon ...
José Domingo Dueñas   +3 more
semanticscholar   +1 more source

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