Results 121 to 130 of about 157,915 (300)

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Legal determinants for running a parish based economic activity

open access: yesKościół i Prawo, 2013
Celem artykułu było ukazanie uwarunkowań prawnych parafii w zakresie wykonywania działalności gospodarczej. Parafia na mocy art. 32 i 20 Konstytucji RP, art. 4 ust. 2 Konkordatu oraz art. 55 ust. 3 ustawy o stosunku Państwa do Kościoła Katolickiego w RP,
Paweł Kaleta
doaj  

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

Efficacy of compressed sensing and deep learning reconstruction for adult female pelvic MRI at 1.5 T

open access: yesEuropean Radiology Experimental
Background We aimed to determine the capabilities of compressed sensing (CS) and deep learning reconstruction (DLR) with those of conventional parallel imaging (PI) for improving image quality while reducing examination time on female pelvic 1.5-T ...
Takahiro Ueda   +9 more
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Letter from Denis Canon Whelan to Hagan

open access: yes, 1926
Holograph letter from Denis Canon Whelan, Parochial House, Kilsheelan, County Tipperary, to (Hagan). Enclosing petition for dispensation (not extant) in a case of consanguinity; explaining that the age of the bride, Miss Nugent, and special family ...

core  

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim   +4 more
wiley   +1 more source

SOBRE EL CANON ESPAÑOL DE LA NARRATIVA ESPAÑOLA DE POSGUERRA (I)

open access: yes, 2015
Hay serios motivos para pensar que uno de los grandes damnificados del canon literario hispánico es el capítulo de la narrativa española de posguerra.
Carmen Morán
core  

Automated chest CT three-dimensional quantification of body composition: adipose tissue and paravertebral muscle

open access: yesScientific Reports
This retrospective study developed an automated algorithm for 3D segmentation of adipose tissue and paravertebral muscle on chest CT using artificial intelligence (AI) and assessed its feasibility.
Akinori Hata   +20 more
doaj   +1 more source

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