Results 101 to 110 of about 119,675 (311)

Frau Hulde – Herodías – Salomé: la construcción del mito en el canon literario europeo [PDF]

open access: yes, 2017
El objeto de esta contribución es examinar la construcción del mito de Salomé en el canon literario europeo. El artículo se centra en el tratamiento literario y artístico de esta figura femenina en los Evangelios, las sagas populares y leyendas ...
Domínguez Macías, Leopoldo
core  

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

open access: yesFEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee   +6 more
wiley   +1 more source

The Religiosity of Adolescents and Young Adults in Malta: Tracing Trajectories

open access: yesReligions
In a country where almost the totality of the native population is baptized and raised in the Catholic Church, recent surveys have shown several inconsistencies, especially among the young who claim that they do not believe.
Paul Galea, Carl-Mario Sultana
doaj   +1 more source

Canon culturel. Canon littéraire. Canon linguistique

open access: yesCalenda, 2017
La Romània propose et offre généreusement à la réflexion de l’Europe (et pas seulement) des modèles canoniques, culturels, littéraires et linguistiques qui se retrouvent autant le long des siècles que dans l’extrême contemporanéité, dans le monde et l’art romanes sous des formes artistiques, communicationnelles et scientifiques différentes.
openaire   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

SOBRE EL CANON ESPAÑOL DE LA NARRATIVA ESPAÑOLA DE POSGUERRA (I)

open access: yes, 2015
Hay serios motivos para pensar que uno de los grandes damnificados del canon literario hispánico es el capítulo de la narrativa española de posguerra.
Carmen Morán
core  

The geriatric canon

open access: yesMonaldi Archives for Chest Disease, 2019
Over the years Geriatrics and gerontology have developed a language shared by most clinicians and researchers who unequivocally defines the health conditions of aging people: one could speak of "geriatric canon", i.e. the set of fundamentals (paradigms, principles, standard reference vocabulary) of geriatric knowledge, the heritage from which they draw
openaire   +4 more sources

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

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