Results 111 to 120 of about 157,915 (300)
Molecular Oncology, EarlyView.Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso +5 more
wiley +1 more source
, 2014 El objetivo de este blog es crear un espacio de reflexión y discusión en torno a los conceptos de "clásico" y "canon". Se trata de tomar conciencia de los procesos que constituyen el corpus de libros que generalmente se identifican con una literatura, y ...
Carmen Morán
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Canon culturel. Canon littéraire. Canon linguistique
Calenda, 2017 La Romània propose et offre généreusement à la réflexion de l’Europe (et pas seulement) des modèles canoniques, culturels, littéraires et linguistiques qui se retrouvent autant le long des siècles que dans l’extrême contemporanéité, dans le monde et l’art romanes sous des formes artistiques, communicationnelles et scientifiques différentes.
openaire +1 more source
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
unboxing the canon - Episode 8: Appropriation and Copying [PDF]
, 2020 In this episode, “Appropriation & Copying,” I take a look at the ways in which artists refer to the work of their predecessors through copying and appropriation. Art instruction uses copying as a method to learn.
Steer, Linda
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Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer
Molecular Oncology, EarlyView.Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba +5 more
wiley +1 more source
Discrete Mathematics, 2009 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
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Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
Molecular Oncology, EarlyView.We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Cadernos de Tradução, 2018 A discussão sobre o status do texto literário traduzido e a posição do tradutor são uma constante na área dos Estudos da Tradução. Temas sensíveis como autoria, autoria do texto traduzido e a posição do texto traduzido no sistema literário de acolhida recebem muita atenção por parte dos pesquisadores, bem como discussões sobre o cânone literário e o ...
openaire +5 more sources