Results 111 to 120 of about 119,675 (311)
FEBS Open Bio, EarlyView.The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley +1 more source
Revisiting the canonicity of canonical triangulations
Theory and Applications of Categories, 2018 Stable derivators provide an enhancement of triangulated categories as is indicated by the existence of canonical triangulations. In this paper we show that exact morphisms of stable derivators induce exact functors of canonical triangulations, and similarly for arbitrary natural transformations. This 2-categorical refinement also provides a uniqueness
openaire +3 more sources
Small RNA pathways in mammalian oocytes
FEBS Open Bio, EarlyView.Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley +1 more source
Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
FEBS Open Bio, EarlyView.PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source
Letter from Denis Canon Whelan to Hagan
, 1926 Holograph letter from Denis Canon Whelan, Parochial House, Kilsheelan, County Tipperary, to (Hagan). Enclosing petition for dispensation (not extant) in a case of consanguinity; explaining that the age of the bride, Miss Nugent, and special family ...
core
FEBS Open Bio, EarlyView.Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
Efficacy of compressed sensing and deep learning reconstruction for adult female pelvic MRI at 1.5 T
European Radiology ExperimentalBackground We aimed to determine the capabilities of compressed sensing (CS) and deep learning reconstruction (DLR) with those of conventional parallel imaging (PI) for improving image quality while reducing examination time on female pelvic 1.5-T ...
Takahiro Ueda +9 more
doaj +1 more source
European Journal of Radiology OpenPurpose: Traditional CT acquisition planning is based on scout projection images from planar anterior-posterior and lateral projections where the radiographer estimates organ locations.
Alexa E. Golbus +7 more
doaj +1 more source
Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
FEBS Open Bio, EarlyView.Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
unboxing the canon - Episode 8: Appropriation and Copying
, 2020 In this episode, “Appropriation & Copying,” I take a look at the ways in which artists refer to the work of their predecessors through copying and appropriation. Art instruction uses copying as a method to learn.
Steer, Linda
core +1 more source