Results 131 to 140 of about 641,970 (337)
The role of lipid metabolism in neuronal senescence
FEBS Open Bio, EarlyView.Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari +2 more
wiley +1 more source
Demonstrations for Children of All Age- The Cork Canon [PDF]
, 1999 Demonstrations are one of the most useful techniques for teaching science to anyone, regardless of age. Demonstrations attract attention and normally make the observer want to learn more about what is happening. This paper reports on The Cork Cannon, one
Thornton, S.
core +1 more source
BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma
FEBS Open Bio, EarlyView.The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru +6 more
wiley +1 more source
Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes
FEBS Open Bio, EarlyView.We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde +3 more
wiley +1 more source
Matching & Information Provision by One-Sided and Two-Sided Platforms [PDF]
, 2011 This paper studies a “market creating” firm (platform) that offers a matching environment by charging an access fee to a population of high and low type users who wish to form a match.
Canon, Carlos
core
The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential
Aging and Cancer, EarlyView.As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley +1 more source
Scientific ReportsThis retrospective study developed an automated algorithm for 3D segmentation of adipose tissue and paravertebral muscle on chest CT using artificial intelligence (AI) and assessed its feasibility.
Akinori Hata +20 more
doaj +1 more source
Now: Music from the musicals 1975 - 2018 [PDF]
, 2018 Musical Theatre performance at The Meteor Theatre Gwen is an opera singer and is joined for an evening of song, by special guests; Courteney Mayall, Alex Pelham-Waerea, Scot Hall, Hannah MacFarlane and Michaela Gilling Accompanied by the incomparable ...
Lyon, Gwen, Sidwell, David
core
A Study on the Articles of the Doctrine of the Perseverance of the Saints in the Canons of the Dort
, 2020 Yoon Seok Lee
openalex +2 more sources
Aging and Cancer, EarlyView.Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source