Results 71 to 80 of about 119,675 (311)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Loder, T.E. Canon. Canon T.E Loder interview, August 11, 1969.

, 1969
Canon Loder was rector of Parish of Grand Falls. He discusses coming to Grand Falls, serving a clergy to logging camps; history of Grand Falls and the pioneer citizens; and his life experiences as a clergyman in a growing, changing Newfoundland ...
Silk, Hiram
core  

The Beginning of the Biblical Canon and Ben Sira

, 2022
The Book of Ben Sira, written in Hebrew in the early second century BCE, is often regarded as containing the earliest references to the canon of the Hebrew Bible / Old Testament.
Brodersen, Alma
core   +1 more source

Fully automatic fossa ovalis segmentation from computed tomography images using deep neural network with atlas-based localization

Informatics in Medicine Unlocked
Background and objective: Information on the location of the fossa ovalis (FO) is necessary for planning interventional procedures that require an inter-atrial septal (IAS) puncture.
Gakuto Aoyama, Toru Tanaka, Yukiteru Masuda, Naoki Matsuki, Ryo Ishikawa, Masahiko Asami, Kiyohide Satoh, Takuya Sakaguchi   +7 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Canon Auto Zoom 518 Super 8 Camera

, 1964
Canon provides imaging, optical, and industrial products, such as lenses, cameras, scanners, medical equipment, printers, and semiconductor manufacturing equipment. In April 1964, Eastman Kodak announced a new 8mm film standard: Super 8.

core  

A Rather Accurate Piano Transcription of Pachelbel’s Canon in D

, 2020
Did you ever want to learn Pachelbel's flagship piece for solo keyboard and found, to your disappointment, that existing arrangements were a little too... non-canonical?
Isaac David
core   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

(Dé)construire le canon

, 2011
Réunissant principalement de jeunes chercheur-e-s, ce séminaire de recherches qui s’inscrit dans l’axe « Traditions et modernités » du CRLC de Paris IV se propose d’interroger, dans une perspective critique et métacritique, les processus historiques ...
Marie-Pierre Harder
core   +1 more source