Results 21 to 30 of about 183,483 (213)
Canonical correlation analysis for gene-based pleiotropy discovery.
PLoS Computational Biology, 2014 Genome-wide association studies have identified a wealth of genetic variants involved in complex traits and multifactorial diseases. There is now considerable interest in testing variants for association with multiple phenotypes (pleiotropy) and for ...
Jose A Seoane +4 more
doaj +1 more source
ANALYSIS OF STUDENT PERFORMANCE BASED ON CANONICAL CORRELATION ANALYSIS
Компютерні системи та інформаційні технологіїThe article examines the application of Canonical Correlation Analysis (CCA) to investigate the relationships between student performance outcomes across different groups of disciplines.
Катерина БЕРЕЗЬКА +3 more
doaj +1 more source
Robust and sparse canonical correlation analysis based L(2,p)-norm
The Journal of Engineering, 2017 The objective function of canonical correlation analysis (CCA) is equivalent to minimising an L(2)-norm distance of the paired data. Owing to the characteristic of L(2)-norm, CCA is highly sensitive to noise and irrelevant features.
Zhong-rong Shi +3 more
doaj +1 more source
Associating Images with Sentences Using Recurrent Canonical Correlation Analysis
Applied Sciences, 2020 Associating images with sentences has drawn much attention recently. Existing methods commonly represent an image by indistinctively describing all its contents in an one-time static way, which ignores two facts that (1) the association analysis can only
Yawen Guo, Hui Yuan, Kun Zhang
doaj +1 more source
Solving the SSVEP Paradigm Using the Nonlinear Canonical Correlation Analysis Approach
Sensors, 2021 This paper presents the implementation of nonlinear canonical correlation analysis (NLCCA) approach to detect steady-state visual evoked potentials (SSVEP) quickly.
Danni Rodrigo De la Cruz-Guevara +2 more
doaj +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Development of Automatic Wheeze Detection Algorithm for Children With Asthma
IEEE Access, 2021 Asthma is a symptom of tracheal obstruction caused by bronchospasm, and it is among the most prevalent chronic obstructive pulmonary diseases. Auscultation is the most commonly used approach for the clinical diagnosis of asthma.
Ho-Chang Kuo +3 more
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source