Results 41 to 50 of about 468,573 (268)
Canonical correlation analysis of high-dimensional data with very small sample support [PDF]
, 2016 This paper is concerned with the analysis of correlation between two high-dimensional data sets when there are only few correlated signal components but the number of samples is very small, possibly much smaller than the dimensions of the data. In such a
Hasija, Tanuj +3 more
core +2 more sources
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Gene-to-metabolite network for biosynthesis of lignans in MeJA-elicited Isatis indigotica hairy root cultures. [PDF]
, 2015 Root and leaf tissue of Isatis indigotica shows notable anti-viral efficacy, and are widely used as "Banlangen" and "Daqingye" in traditional Chinese medicine.
Chen, Junfeng +9 more
core +2 more sources
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Indirect caffeine modeling in an urban river
Revista Ambiente & Água, 2022 Caffeine is used worldwide as a chemical tracer to identify anthropic pressures on urban water resources. Nevertheless, its quantification demands great financial investments.
Luis Otávio Miranda Peixoto +3 more
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Person re-identification by robust canonical correlation analysis [PDF]
, 2015 Person re-identification is the task to match people in surveillance cameras at different time and location. Due to significant view and pose change across non-overlapping cameras, directly matching data from different views is a challenging issue to ...
An, L, Bhanu, B, Yang, S
core +2 more sources
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
A New Robust Deep Canonical Correlation Analysis Algorithm for Small Sample Problems
IEEE Access, 2019 As a nonlinear feature learning method, deep canonical correlation analysis (DCCA) has got a great success in computer vision. Compared with kernel methods, deep neural networks can more easily process large amounts of training data and do not require ...
Yan Liu, Yun Li, Yun-Hao Yuan, Hui Zhang
doaj +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source