Results 31 to 40 of about 183,483 (213)
Indirect caffeine modeling in an urban river
Revista Ambiente & Água, 2022 Caffeine is used worldwide as a chemical tracer to identify anthropic pressures on urban water resources. Nevertheless, its quantification demands great financial investments.
Luis Otávio Miranda Peixoto +3 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
A New Robust Deep Canonical Correlation Analysis Algorithm for Small Sample Problems
IEEE Access, 2019 As a nonlinear feature learning method, deep canonical correlation analysis (DCCA) has got a great success in computer vision. Compared with kernel methods, deep neural networks can more easily process large amounts of training data and do not require ...
Yan Liu, Yun Li, Yun-Hao Yuan, Hui Zhang
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Image dehazing using two‐dimensional canonical correlation analysis
IET Computer Vision, 2015 Image dehazing is an important issue that interests both image processing and computer vision. In this study, image dehazing is modelled as an example‐based learning problem, and a novel dehazing algorithm using two‐dimensional (2D) canonical correlation
Liqian Wang, Liang Xiao, Zhihui Wei
doaj +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
In silico drug repositioning based on integrated drug targets and canonical correlation analysis
BMC Medical Genomics, 2022 Background Besides binding to proteins, the most recent advances in pharmacogenomics indicate drugs can regulate the expression of non-coding RNAs (ncRNAs).
Hailin Chen, Zuping Zhang, Jingpu Zhang
doaj +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Socio-Economic and Urbanization Profiles of Internal Migration in Egypt: A Canonical Correlation Analysis [PDF]
المجلة المصرية للسکـان وتنظيم الأسرة, 1993 Data on in and out migration in Egypt by governorate and on variables believed to interact with migration are examined. The purpose is to identify the dimensions through which the basic demographic phenomenon can be rationally structured.
.M. G El-Rouby
doaj +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source