Results 51 to 60 of about 183,483 (213)
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
A survey on canonical correlation analysis based multi-view learning
智能科学与技术学报, 2022 Multi-view learning (MVL) is a strategy for fusing data from different sources or subsets.Canonical correlation analysis (CCA) is very important in MVL, whose main idea is to maximize the correlation of different views.The traditional CCA can only ...
Chenfeng GUO, Dongrui WU
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A whitening approach to probabilistic canonical correlation analysis for omics data integration
BMC Bioinformatics, 2019 Background Canonical correlation analysis (CCA) is a classic statistical tool for investigating complex multivariate data. Correspondingly, it has found many diverse applications, ranging from molecular biology and medicine to social science and finance.
Takoua Jendoubi, Korbinian Strimmer
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Türkiye Tarımsal Araştırmalar Dergisi, 2020 This study was conducted to estimate the relationships between the ultrasonic measurements and carcass characteristics of Akkaraman lambs at different intensive feeding periods with a multivariate correlation (canonical).
Yasin ALTAY +2 more
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Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Cluster analysis of replicated alternative polyadenylation data using canonical correlation analysis
BMC Genomics, 2019 Background Alternative polyadenylation (APA) has emerged as a pervasive mechanism that contributes to the transcriptome complexity and dynamics of gene regulation. The current tsunami of whole genome poly(A) site data from various conditions generated by
Wenbin Ye +6 more
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Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Research on the Relationship between Well-being and Personality Traits in the Elderly Based on Canonical Correlation Analysis [PDF]
Zhongguo quanke yixueBackground With the population ages, the mental health of the elderly has become a hot topic of concern for the whole society. Previous studies have shown that mental health problems in the elderly are closely related to well-being, while personality ...
ZHOU Yujie, LIU Huanting, WAN Chonghua, GAN Qihui, XIAO Junhui, LIU Yuxi
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Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
A Jacobi–Davidson Method for Large Scale Canonical Correlation Analysis
Algorithms, 2020 In the large scale canonical correlation analysis arising from multi-view learning applications, one needs to compute canonical weight vectors corresponding to a few of largest canonical correlations.
Zhongming Teng, Xiaowei Zhang
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