Results 71 to 80 of about 24,058,587 (288)
Canonical correlation analysis of main breeding traits for Landrace
浙江大学学报. 农业与生命科学版, 2000 The analysis of canonical correlation for 14 traits in 3 groups was carried out in the study. The growth and development traits composed of 4 traits, body size 6 traits and fat thickness and appearance 4 traits.
XU Ning-ying +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Detection for gene-gene co-association via kernel canonical correlation analysis
BMC Genetics, 2012 Background Currently, most methods for detecting gene-gene interaction (GGI) in genomewide association studies (GWASs) are limited in their use of single nucleotide polymorphism (SNP) as the unit of association.
Yuan Zhongshang +6 more
doaj +1 more source
REPRESENTATION-CONSTRAINED CANONICAL CORRELATION-ANALYSIS: A HYBRIDIZATION OF CANONICAL CORRELATION AND PRINCIPAL COMPONENT ANALYSIS [PDF]
The classical canonical correlation analysis is extremely greedy to maximize the squared correlation between two sets of variables. As a result, if one of the variables in the dataset-1 is very highly correlated with another variable in the dataset-2 ...
Sudhanshu K MISHRA
core
, 1999 Analyses customer satisfaction with mail-order speciality foods in the UK and examines the relationship between satisfaction with eight attributes of mail-order speciality food and their association with overall satisfaction and likelihood of future ...
Mai, L.W., Ness, M.R.
core +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Türkiye Tarımsal Araştırmalar Dergisi, 2020 This study was conducted to estimate the relationships between the ultrasonic measurements and carcass characteristics of Akkaraman lambs at different intensive feeding periods with a multivariate correlation (canonical).
Yasin ALTAY +2 more
doaj +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
A whitening approach to probabilistic canonical correlation analysis for omics data integration
BMC Bioinformatics, 2019 Background Canonical correlation analysis (CCA) is a classic statistical tool for investigating complex multivariate data. Correspondingly, it has found many diverse applications, ranging from molecular biology and medicine to social science and finance.
Takoua Jendoubi, Korbinian Strimmer
doaj +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source