Results 21 to 30 of about 29,917 (203)
On the Completeness of the Set of Classical W-Algebras Obtained from DS Reductions
, 1993 We clarify the notion of the DS --- generalized Drinfeld-Sokolov --- reduction approach to classical ${\cal W}$-algebras. We first strengthen an earlier theorem which showed that an $sl(2)$ embedding ${\cal S}\subset {\cal G}$ can be associated to every ...
A. Bilal +44 more
core +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Hamiltonian systems of hydrodynamic type in 2 + 1 dimensions
, 2007 We investigate multi-dimensional Hamiltonian systems associated with constant Poisson brackets of hydrodynamic type. A complete list of two- and three-component integrable Hamiltonians is obtained. All our examples possess dispersionless Lax pairs and an
A. Moro +23 more
core +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Weak splittings of quotients of Drinfeld and Heisenberg doubles
, 2014 We investigate the fine structure of the simplectic foliations of Poisson homogeneous spaces. Two general results are proved for weak splittings of surjective Poisson submersions from Heisenberg and Drinfeld doubles. The implications of these results are
A. A. Belavin +16 more
core +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
An irreducibility criterion for group representations, with arithmetic applications
, 2010 We prove a criterion for the irreducibility of an integral group representation \rho over the fraction field of a noetherian domain R in terms of suitably defined reductions of \rho at prime ideals of R.
Longo, M., Vigni, S.
core +2 more sources
On the determination of the dilaton-antisymmetric tensor couplings in supergravity theories [PDF]
, 1993 A new approach is provided to determine the dilaton--antisymmetric tensor coupling in a supergravity theory by considering the static supersymmetric field configuration around a super extended object, which is consistently formulated in a curved ...
Achucarro +16 more
core +3 more sources