Results 61 to 70 of about 3,906,604 (254)

Development of an indirect immunofluorescence assay for PCV3 antibody detection based on capsid protein

open access: yesAnimal Diseases, 2021
Porcine circovirus type 3 (PCV3) is a novel porcine circovirus associated with porcine dermatitis and nephritis syndrome (PDNS), reproductive failure, and multisystemic inflammation.
Lun Yao   +9 more
doaj   +1 more source

Mitochondrial Localization Signal of Porcine Circovirus Type 2 Capsid Protein Plays a Critical Role in Cap-Induced Apoptosis

open access: yesVeterinary Sciences, 2021
Porcine circovirus 2 (PCV2), considered one of the most globally important porcine pathogens, causes postweaning multisystemic wasting syndrome (PMWS). This virus is localized in the mitochondria in pigs with PMWS. Here, we identified, for the first time,
Wanting Yu   +9 more
doaj   +1 more source

CARMIL Is a Bona Fide Capping Protein Interactant [PDF]

open access: yesJournal of Biological Chemistry, 2004
CARMIL, also known as Acan 125, is a multidomain protein that was originally identified on the basis of its interaction with the Src homology 3 (SH3) domain of type I myosins from Acanthamoeba. In a subsequent study of CARMIL from Dictyostelium, pull-down assays indicated that the protein also bound capping protein and the Arp2/3 complex.
Kirsten, Remmert   +5 more
openaire   +2 more sources

Mathematical and Computational Modelling of Ribosomal Movement and Protein Synthesis: an overview [PDF]

open access: yes, 2012
Translation or protein synthesis consists of a complex system of chemical reactions, which ultimately result in decoding of the mRNA and the production of a protein.
von der Haar, Tobias   +1 more
core   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

Dietary fishmeal replacement by Clostridium autoethanogenum protein meal influences the nutritional and sensory quality of turbot (Scophthalmus maximus) via the TOR/AAR/AMPK pathways

open access: yesAnimal Nutrition
Clostridium autoethanogenum protein (CAP) is a promising protein source for aquaculture; however, how CAP influences fish quality is worth extensive research.
Zezheng Qi   +4 more
doaj   +1 more source

Cold atmospheric plasma treatment enhances recombinant model protein production in yeast Pichia pastoris

open access: yesScientific Reports, 2023
Cold atmospheric pressure plasma (CAP) has been described as a novel technology with expanding applications in biomedicine and biotechnology. In the present study, we provide a mildly stressful condition using non-lethal doses of CAP (120, 180, and 240 s)
Zeinab Kabarkouhi   +3 more
doaj   +1 more source

CAPS: coevolution analysis using protein sequences [PDF]

open access: yesBioinformatics, 2006
Abstract Summary: Coevolution Analysis using Protein Sequences (CAPS) is a PERL based software that identifies co-evolution between amino acid sites. Blosum-corrected amino acid distances are used to identify amino acid co-variation. The phylogenetic sequence relationships are used to remove the phylogenetic and stochastic dependencies ...
Mario A. Fares, David McNally
openaire   +3 more sources

RAM function is dependent on Kapβ2-mediated nuclear entry [PDF]

open access: yes, 2014
Eukaryotic gene expression is dependent on the modification of the first transcribed nucleotide of pre-mRNA by the addition of the 7-methylguanosine cap.
Gonatopoulos-Pournatzis, Thomas   +1 more
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

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