Results 91 to 100 of about 4,324,014 (329)
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Orthopaedic SurgeryObjectives Currently, there are various surgical options for the treatment of lateral ankle sprains, and deciding which surgical option to use is a question worth considering.
Qingfeng Shao +8 more
doaj +1 more source
APPROPRIATENESS OF GIFTED CHILDREN SOCIALIZATION IN CONTEMPORARY SOCIOCULTURAL CONDITIONS [PDF]
Sovremennye Issledovaniâ Socialʹnyh Problem, 2012 The article opens general appropriateness of one of the most important directions in working with gifted children that is socialization; it substantiatesappropriateness as an axiom scheme, providing successfulness of the examined process; authors ...
Rimma Litvak, Tatyana Bondarchuk
doaj
Glossa, 2018 I propose a classification of dispositions according to two parameters: (i) whether their argument is a causer, and (ii) whether they are (almost) always realized or only sometimes realized.
Ariel Cohen
doaj +2 more sources
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
BMC Musculoskeletal DisordersBackground At present, the modified suture augmentation (MSA) repair and the InternalBrace™ (IB) reconstruction techniques are commonly used for the treatment of chronic ankle instability (CAI).
Zifeng Wu +7 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
CBRN EOD capability as a current challenge for Czech Armed Forces Chemical Corps
Vojenské rozhledy, 2015 The article describes CBRN EOD capability, which is one of the developed areas within the scope of the Czech Armed Forces Chemical Corps. It depicts CBRN EOD in the context of operational use of chemical troops, introduces an option of appropriate task ...
Radim Zahradníček, Zdeněk Skaličan
doaj +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
BMC Musculoskeletal DisordersBackground A coracoid process fracture combined with an acromioclavicular (AC) joint dislocation is an uncommon injury that typically causes significant pain and limits shoulder movement.
Weizhao Xie +3 more
doaj +1 more source