Results 141 to 150 of about 638,237 (304)

Poverty and Wealth Reporting of the German Government: Approach, Lessons and Critique [PDF]

The Capability Approach has been adopted as a theoretical framework for official Poverty and Wealth Reports by the German government. For the first time, this paper provides information on the use of the Capability Approach in this reporting process to ...
Juergen Volkert, Christian Arndt
core  

Development and Poverty Dynamics in Severe Mental Illness: A Modified Capability Approach in the Chinese Context. [PDF]

Int J Environ Res Public Health, 2022
Yu YH, Peng MM.
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Organizational Adoption of Capability Management

, 2018
The introduction of capability management into an enterprise and establishment of a supporting organization structure, like in many other management approaches, affect different parts of the enterprise and require careful preparation.
Kurt Sandkuhl, Stirna, Janis,, Janis Stirna, Sandkuhl, Kurt, Sandkuhl, Kurt,   +4 more
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Ecosystem effects on well-being: More than just "benefits"? Looking at ecosystem services through the capability approach [PDF]

Conceptual discussions on the impacts of ecosystem services (ESS) on human well-being have largely been boiled down to limits and applications of their monetisation.
Polishchuk, Yuliana, Rauschmayer, Felix
core  

Sustainable development, capabilities, hegemonic forces and social risks: extending the capability approach to promote resilience against social inequalities

, 2023
YesThe capability approach (CA), while originally regarded as a ‘thin’ framework relating to an individual’s ‘States’, has been progressively deployed in wider spaces of social welfare and policy development.
Ikejiaku, Brian V., Jogie, M.
core  

Towards effective and sustainable global academic partnerships through a maturity model informed by the capability approach. [PDF]

Global Health, 2021
Fekadu A, Assefa E, Tesfaye A, Hanlon C, Adefris B, Manyazewal T, Newport MJ, Davey G.   +7 more
europepmc   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Mapping sustainable development in a capability perspective [PDF]

The importance of the notion of sustainable development has been advocated, among others, by Amartya Sen. In Sen’s view it is necessary to depart from the general strategy of defining sustainable development only in terms of fulfilment of needs and to ...
Enzo Di Giulio, Marco Grasso
core