Results 131 to 140 of about 638,237 (304)
A Capability Approach to worker dignity under Algorithmic Management. [PDF]
Ethics Inf Technol, 2022 Lamers L, Meijerink J, Jansen G, Boon M.
europepmc +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
A Study on Dynamic Capability Approach
, 2012 The concept of dynamic capability has emerged as a complement to the resource-based View (RBV) as an attempt to explain competitive advantage in a rapidly changing environment.
石坂, 庸祐 +2 more
core +1 more source
Sustainable competitive advantage in maternal and child health institutions: a dynamic capability approach. [PDF]
Ann Oper Res, 2022 Yuan H, Ferreira FAF.
europepmc +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Gender Auditing in a Capability Approach [PDF]
Feminist studies have developed several tools to assess the gender impact of public policy and, in particular, of public budgets. We introduce an innovative approach to gender auditing of public budgets inspired by the capability approach.
Diego Lanzi +2 more
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Capability Index: Applying a Fuzzy-Based Decision-Making Method to Evaluate Social Inclusion in Urban Areas Using the Capability Approach. [PDF]
Soc Indic Res, 2023 Azmoodeh M, Haghighi F, Motieyan H.
europepmc +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
A Capability Approach for Official German Poverty and Wealth Reports: Conceptual Background and First Empirical Results [PDF]
The majority of the literature related to Amartya Sen´s Capability Approach (CA) has been devoted to questions of development and developing countries. In this paper, however, with a theoretical concept and first empirical results at hand, we shed some ...
Christian Arndt, Jürgen Volkert
core
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source