Results 111 to 120 of about 638,237 (304)

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Scoring System for the Japanese Version of the ICECAP-A [Corrigendum]

open access: yesPsychology Research and Behavior Management
Sado M, Nagashima K, Koreki A. Psychol Res Behav Manag. 2025;18:703–717. The authors have advised that the following reference to the Japanese version of ICECAP-A was missed from page 717 of the published proof. 52. Kobayashi H. the Implementation
Sado M, Nagashima K, Koreki A
doaj  

「學習化導向」作為一種教育治理技術:面對AI時代的能力取向教育社會學 “Learnification Orientation” as a Technique of Educational Governance: Capabilities-Based Sociology of Education for the AI Era

open access: yes臺灣教育社會學研究
面對隨著AI技術、大數據和演算法的廣泛應用,出現「學習化導向」現象,教育治理模式也發生顯著變化。本研究首先分析數據治理與AI對於學校教育的挑戰;進而討論全球化背景下智慧學習是如何影響教育公平和終身學習,並對「學習化導向」的工具化傾向提出批判性反思;接著再轉向晚期Foucault治理性與美學式的自我存有,分析教育機構作為社會控制和知識生產的重要場域,並探討規訓權力與生命權力面對AI技術控制的可能解釋;最後則分析能力取向的核心內涵,並將之與Parsons、Giddens與晚期Foucault等觀點加以整合 ...
王俊斌 Chunping Wang
doaj   +1 more source

Capability Approach and Inclusion: Developing a Context Sensitive Design for Biobased Value Chains. [PDF]

open access: yesJ Agric Environ Ethics, 2023
Asveld L   +3 more
europepmc   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Re-conceptualising sustainable development on the basis of the capability approach: A model and its difficulties [PDF]

open access: yes
This paper sketches a re-conceptualisation of sustainable development (SD) on the basis of the capability approach (CA). The notion sustainable development was developed as a compromise in a political process and has been re-interpreted (some say ...
Leßmann, Ortrud, Rauschmayer, Felix
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Designing accessible educational experiences. An analysis through the lenses of Capability Approach

open access: yes
reservedNel mondo odierno in rapido cambiamento, l'educazione si confronta con una sfida critica: andare oltre la semplice acquisizione di conoscenze e responsabilizzare gli individui a prosperare in una società complessa e diversificata.
D'ADAM, ADELE
core  

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