Results 101 to 110 of about 11,911,049 (290)

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Exploring occupational therapy interventions in homeless settings in Tshwane

open access: yesHealth SA Gesondheid: Journal of Interdisciplinary Health Sciences
Background: In South Africa, the national lockdown was both a challenge and an opportunity to address health-related issues of homelessness. While initial emergency responses in Tshwane focused on basic needs and medical intervention, the need for more ...
Sarah Ainsworth   +2 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Scoring System for the Japanese Version of the ICECAP-A [Corrigendum]

open access: yesPsychology Research and Behavior Management
Sado M, Nagashima K, Koreki A. Psychol Res Behav Manag. 2025;18:703–717. The authors have advised that the following reference to the Japanese version of ICECAP-A was missed from page 717 of the published proof. 52. Kobayashi H. the Implementation
Sado M, Nagashima K, Koreki A
doaj  

「學習化導向」作為一種教育治理技術:面對AI時代的能力取向教育社會學 “Learnification Orientation” as a Technique of Educational Governance: Capabilities-Based Sociology of Education for the AI Era

open access: yes臺灣教育社會學研究
面對隨著AI技術、大數據和演算法的廣泛應用,出現「學習化導向」現象,教育治理模式也發生顯著變化。本研究首先分析數據治理與AI對於學校教育的挑戰;進而討論全球化背景下智慧學習是如何影響教育公平和終身學習,並對「學習化導向」的工具化傾向提出批判性反思;接著再轉向晚期Foucault治理性與美學式的自我存有,分析教育機構作為社會控制和知識生產的重要場域,並探討規訓權力與生命權力面對AI技術控制的可能解釋;最後則分析能力取向的核心內涵,並將之與Parsons、Giddens與晚期Foucault等觀點加以整合 ...
王俊斌 Chunping Wang
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

The Capability Approach [PDF]

open access: yes, 2008
The capability approach developed by Nobel Laureate Amartya Sen has become an important new paradigm in thinking about development. However, despite its theoretical and philosophical attractiveness, it has been less easy to measure or to translate into policy. This volume addresses these issues in the context of poverty and justice. Part I offers a set
openaire   +1 more source

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