Results 121 to 130 of about 254,019 (304)
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
, 2011 Process capability indices had been widely used to evaluate the process performance. The process capability index proposed by Chan et al. [2] does take into account of the proximity of the process mean to the target value T for asymmetric tolerance. For
Wu, Shu-Fei
core
Measuring early child development in low and middle income countries: Investigating the validity of the early Human Capability Index. [PDF]
SSM Popul Health, 2020 Sincovich A +5 more
europepmc +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Composite Indices of Human Well-being: Past, Present, and Future [PDF]
human well-being, composite well-being indices, income per capita, Human Development Index, Physical Quality of Life ...
Noorbakhsh, Farhad, McGillivray, Mark
core
A new asymmetric bounded loss-based process capability index [PDF]
, 2010 Process capability indices such as Cp, Cpk, Cpu and Cpl are common metrics to evaluate and predict the performance of a process. Although higher process capability indices indicate higher process “quality”, but a high quality process does not necessarily
Ismail, Yusof +3 more
core
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Development of Fuzzy Service Capability Index in Supplier Selection
, 2010 [[abstract]]Supplier selection is very important and complex problem for the businessman. The master have to make the correct decision before consider the different evaluation guideline. The fuzzy linguistic variable transformed to a crisp number through
Chen, Chia-Hui
core
SystemsThe optoelectronic information industry is a strategic high-tech industry with wide applications. Compared with developed countries, China’s optoelectronic information industry presents a situation of “strong application and weak technology”.
Zhenzhao Li +4 more
doaj +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source