Results 111 to 120 of about 17,024,608 (281)
Cell surface CD11c as a neutrophil aging marker molecule
FEBS Open Bio, EarlyView.Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki +5 more
wiley +1 more source
A capability maturity model for data acquisition and utilisation [PDF]
, 2009 In this paper we adopt a capability maturity management (CMM) approach to the issue of data management and utilisation. Applying a CCM approach in conjunction with a newly developed engineering data typology allows engineering managers and practitioners
Chang, Artemis, Murphy, Glen D.
core
Tourism and HospitalityArtificial intelligence (AI) is reshaping the hospitality industry at an unprecedented pace. However, existing hospitality research has overwhelmingly concentrated on customer-facing applications, including service robots, chatbots, personalization, and ...
Georgios Konstantopoulos +3 more
doaj +1 more source
BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells
FEBS Open Bio, EarlyView.BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley +1 more source
Many organisations in the Greater China Region (GCR) invest significant resources in their enterprise resource planning (ERP) systems, integrating or embedding advanced BA functionalities. The justification for this research is based on the importance of
Wong, Wai Yip Freddy
core +1 more source
Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells
FEBS Open Bio, EarlyView.Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla +10 more
wiley +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Tratamento de documento textuais estruturados no ambiente SEA [PDF]
, 2004 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-graduação em Ciência da ComputaçãoEste trabalho propõe solução para uma deficiência encontrada em ambientes de desenvolvimento de software em geral: a ...
Bonfim, Viviane Duarte
core
Motorola Secure Software Development Model [PDF]
Journal of Systemics, Cybernetics and Informatics, 2008 In today's world, the key to meeting the demand for improved security is to implement repeatable processes that reliably deliver measurably improved security.
Francis Mahendran, Margaret Nadworny
doaj
Aging and Cancer, EarlyView.Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi +3 more
wiley +1 more source