Results 101 to 110 of about 138,351 (294)
FEBS Open Bio, EarlyView.Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold +11 more
wiley +1 more source
Physics-Informed Machine Learning for Intelligent Gas Turbine Digital Twins: A Review
EnergiesThis review surveys recent progress in hybrid artificial intelligence (AI) approaches for gas turbine intelligent digital twins, with an emphasis on models that integrate physics-based simulations and machine learning.
Hiyam Farhat, Amani Altarawneh
doaj +1 more source
Acta Scientiarum: Technology, 2009 Em Micro e Pequenas Empresas de Software (MPEs), geralmente, não há um processo sistemático de desenvolvimento de software. Um dos motivos é que essas empresas consideram os processos tradicionais extensos.
Francisco Virginio Maracci +4 more
doaj +1 more source
A model proposal for integrated management systems maturity assessment [PDF]
, 2014 Maturity models enabling the assessment of integrated management systems (IMS) are crucial in order to provide a comparison between IMS from different companies. This paper intends to report the efforts made and the methodologies followed to develop an
Arezes, P. +2 more
core
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
InspirationData security is an essential component of ERP system management, particularly given the increasing cyber dangers in the digital age. This study assesses the maturity of ERP-based information security at PT BroilerX Yogyakarta using the ISO/IEC 27001 ...
Puji Hastuti +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand +2 more
wiley +1 more source
A Digital Sustainability Maturity Framework for Assessing Industry 4.0 and ESG Integration
Production Engineering ArchivesThe growing convergence of digital transformation and sustainability requirements necessitates the development of integrated analytical frameworks that enable the simultaneous assessment of an organization’s technological maturity and its ESG maturity ...
Ingaldi Manuela, Ulewicz Robert
doaj +1 more source
Combining Individual and Organizational Capabilities: An Integrated Maturity Model for Ambidexterity [PDF]
Proceedings of the Annual Hawaii International Conference on System Sciences, 2021 Rocco Xaver Richard Huber +2 more
openaire +2 more sources
FEBS Open Bio, EarlyView.A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti +3 more
wiley +1 more source