Results 81 to 90 of about 10,614 (294)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Wildfire Early Warning Systems: A Multisensor and Predictive Modelling Comparison Across Countries with a Canadian Perspective [PDF]

open access: yesThe International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences
This study evaluates wildfire early warning systems (EWS) across fifteen countries spanning four World Bank income tiers (high, upper-middle, lower-middle, and low) using a two-parameter framework: P1 (multi-sensor satellite integration) and P2 (hotspot ...
A. Sharma   +5 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Relationship between PDP maturity and ISO certification in the food industry

open access: yesGestão & Produção
Food companies have been seeking certification of their Product Development Processes (PDP) as a symbol of quality, however, few are prepared to obtain it.
Lígia de Oliveira Franzosi   +1 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Project Management Maturity Integration based on Capability Maturity Model Integration

open access: yes, 2013
DISSERTATION WITH DISTINCTIONSoftware development is an industry sector which is typified by rapid change and iterative progress. However it is also considered as being leading edge in terms of effective project management because of the cost, resource ...
Ghazal, Taher
core  

From tumor‐centric to ecosystem‐based hypotheses in brain tumor research and care

open access: yesMolecular Oncology, EarlyView.
Primary brain tumors, whether in adults or children, present a major challenge because of their dramatic prognosis and the ongoing lack of efficient therapeutic approaches. In recent years, a shift has occurred from tumor‐centric concepts to a more holistic view of these tumors as dynamic ecosystems.
Julie Gavard   +8 more
wiley   +1 more source

Model Tailoring to Implement CMMI for Minor-Enterprise in Taiwan-A Case Study of Outsourcing for Software Project

open access: yes, 2009
[[abstract]]Minor-Enterprises in Taiwan tend to family-hereditary style, and their professional techniques and business management concepts are also conservative.
Wu Shyh-Chin
core  

Enhancing Extreme Programming (XP) Adoption Through SAMAM: A Scalable Agile Maturity Assessment Model Based on Industry Best Practices

open access: yesIEEE Access
The adoption of Extreme Programming (XP), a widely recognized Agile methodology, faces numerous barriers that hinder its successful implementation in software development organizations.
Muhammad Faisal Abrar   +6 more
doaj   +1 more source

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