Results 61 to 70 of about 10,614 (294)

Developing Digital Service Transformation Maturity Model in Public Sector

IEEE Access
Digital service transformation involves developing or enhancing digital service products within the scope of business transformation. The primary goal is to create or enhance value through the integration of information technology, computing ...
Naufal Fahmi Zakiuddin, Sawung Murdha Anggara, Suhardi   +2 more
doaj   +1 more source

A Maturity Model for Higher Education Institutions [PDF]

Journal of Spatial and Organizational Dynamics, 2013
The adoption of business process improvement strategies is currently a concern of most organizations. The quest for the benefits of this improvement on resource optimization and the responsiveness of the organizations has raised several proposals for ...
Duarte Duarte, Paula Ventura Martins
doaj  

استعراض أهم نماذج نضج إدارة المعرفة: دراسة تحليلية A Review of Key Knowledge Management Maturity Models : An Analytical Study [PDF]

Maǧallaẗ Kulliyyaẗ al-Luġaẗ al-'arabiyyaẗ bi-Assiut
 هدفت الورقة الحالية إلى التركيز على نماذج نضج إدارة المعرفة , وتم استعراض تحليلي وتوصيات للتطبيق في المنظمات, وتناولت التساؤل الرئيس في الدراسة وهو ما نموذج نضج إدارة المعرفة المفضل لدى المؤسسات؟اعتمدت الورقة  الحالية على المنهج الوثائقي؛ وهو المنهج ...
وئام بنت عماد قادري, أ.د.ماجدة عزت غريب   +1 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Tratamento de documento textuais estruturados no ambiente SEA [PDF]

, 2004
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-graduação em Ciência da ComputaçãoEste trabalho propõe solução para uma deficiência encontrada em ambientes de desenvolvimento de software em geral: a ...
Bonfim, Viviane Duarte
core  

An Evolutionary Game Approach to Multi-Technology Synergy in Logistics Information Sharing for Smart Supply Chains

IEEE Access
Logistics information sharing plays a pivotal role in fostering efficient collaboration within the smart supply chain. With the deepening integration of digital technologies such as the Internet of Things (IoT), blockchain, and Artificial Intelligence ...
Ying Zhao, Ya-Juan Yang, Bing Luo
doaj   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

Modelo de maturidade logística para empresas industriais de grande porte [PDF]

, 2012
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-Graduação em Engenharia de Produção, Florianópolis, 2012A logística se tornou um meio pelo qual as empresas conseguem entregar maior valor aos seus clientes e ...
Follmann, Neimar
core  

α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates

FEBS Letters, EarlyView.
Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino, Giuliana Fusco, Alfonso De Simone   +2 more
wiley   +1 more source