Results 61 to 70 of about 387,699 (289)

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Calculations of Electric Capacitance in Carbon and BN Nanotubes, and Zigzag Nanographite (BN, BCN) Ribbons

, 2005
Electronic states in nanographite ribbons with zigzag edges are studied using the extended Hubbard model with nearest neighbor Coulomb interactions. The electronic states with the opposite electric charges separated along both edges are analogous as ...
Dürkop, Fujita, Iijima, Kikuo Harigaya, Lemay, Saito, Terrones, Wakabayashi, Yamashiro   +8 more
core   +1 more source

Whole‐Body Pattern of Muscle Degeneration and Progression in Sarcoglycanopathies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize whole‐body intramuscular fat distribution pattern in patients with sarcoglycanopathies and explore correlations with disease severity, duration and age at onset. Methods Retrospective, cross‐sectional, multicentric study enrolling patients with variants in one of the four sarcoglycan genes who underwent whole‐body ...
Laura Costa‐Comellas, Mauro Monforte, Angel Sanchez‐Montañez, Penélope Romero‐Duque, Elena Pegoraro, Jordi Díaz‐Manera, Dmitry Vlodavets, Lorenzo Maggi, Marco Moscatelli, Adele D‘Amico, Montse Olivé, Jorge Alonso‐Pérez, Giacomo Comi, José Miguel Escudero‐Fernández, Gabriela S. Urcuyo, Anna Pichiecchio, Angela Berardinelli, Kristl G. Claeys, Claudio Bruno, Chiara Panicucci, Sara Bortolani, Eleonora Torchia, Enzo Ricci, Soledad Monges, Jorge A. Bevilacqua, Jorge Diaz‐Jara, Maggie C. Walter, Simone Thiele, Nicoline Løkken, John Vissing, Susana Quijano‐Roy, Robert Y. Carlier, Nicol C. Voermans, Chiara Marini‐Bettolo, Michela Guglieri, Volker Straub, Lea Leonardis, Francina Munell, David Gómez‐Andrés, Giorgio Tasca   +39 more
wiley   +1 more source

Capacitated vertex covering [PDF]

Journal of Algorithms, 2003
Summary: In this paper we study the capacitated vertex cover problem, a generalization of the well-known vertex cover problem. Given a graph \(G=(V,E)\) with weights on the vertices, the goal is to cover all the edges by picking a cover of minimum weight from the vertices. When we pick a copy of a vertex, we pay the weight of the vertex and cover up to
Guha, Sudipto, Hassin, Refael, Khuller, Samir, Or, Einat   +3 more
openaire   +2 more sources

Constant-amplitude RC oscillator [PDF]

, 1970
Sinusoidal oscillator has a frequency determined by resistance-capacitance /RC/ values of two charge control devices and a constant-amplitude voltage independent of frequency and RC values.
Kerwin, W. J., Westbrook, R. M.
core   +1 more source

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz, Christopher H. Thompson, Linda C. Laux, Alfred L. George Jr.   +3 more
wiley   +1 more source

Radiation effects in polycarbonate capacitors [PDF]

Nuclear Technology and Radiation Protection, 2009
The aim of this paper is to examine the influence of neutron and gamma irradiation on the dissipation factor and capacitance of capacitors with polycarbonate dielectrics.
Vujisić Miloš, Stanković Koviljka, Dolićanin Edin, Jovanović Bojan   +3 more
doaj   +1 more source

Capacitative Calcium Entry [PDF]

Physiology, 1998
Capacitative Ca2+ entry is a recently discovered Ca2+ entry pathway that is activated on depletion of intracellular Ca2+ stores, providing an avenue for store refilling. Despite recent progress in elucidating the capacitative Ca2+ entry pathway, the mysteries of its molecular identity, its biophysical properties, and the store depletion signal remain.
Jaclyn R., Holda, Andrey, Klishin, Marina, Sedova, Jörg, Hüser, Lothar A., Blatter   +4 more
openaire   +2 more sources

Programmable electronic synthesized capacitance [PDF]

, 1987
A predetermined and variable synthesized capacitance which may be incorporated into the resonant portion of an electronic oscillator for the purpose of tuning the oscillator comprises a programmable operational amplifier circuit.
Kleinberg, Leonard L.
core   +1 more source

Full capacitance matrix of coupled quantum dot arrays: static and dynamical effects

, 1996
We numerically calculated the full capacitance matrices for both one-dimensional (1D) and two-dimensional (2D) quantum-dot arrays. We found it is necessary to use the full capacitance matrix in modeling coupled quantum dot arrays due to weaker screening ...
Bakhvalov,, C. B. Whan, Duruöz,, Geigenmüller, J. White, Kemerink, Likharev, Middleton, Mooij,, Nabor,, Sakamoto,, T. P. Orlando, Waugh,   +12 more
core   +1 more source