Results 101 to 110 of about 1,559,477 (277)
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
The influence of external factors on production systems in the conditions of a recession
Путеводитель предпринимателя, 2020 The article is devoted to organizational, technological and other changes occurring in the medium and large production systems in conditions of economic contraction.
S. G. Kamshilov
doaj
Tobacco Induced Diseases, 2018 Background and challenges to implementation Hungary produced the greatest progress on the Tobacco Control Scale among 34 European countries in recent years, due to its tobacco control policies.
Tamás Joó +6 more
doaj +1 more source
Quantum Indeterminacy, Polar Duality, and Symplectic Capacities [PDF]
, 2013 The notion of polarity between sets, well-known from convex geometry, is a geometric version of the Fourier transform. We exploit this analogy to propose a new simple definition of quantum indeterminacy, using what we call "hbar-polar quantum pairs ...
de Gosson, Maurice A.
core
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Classes of Measures Generated by Capacities
, 2006 We introduce classes of measures in the half-space $\mathbf{R}^{n+1}_+,$ generated by Riesz, or Bessel, or Besov capacities in $\mathbf{R}^n$, and give a geometric characterization as Carleson-type ...
Dafni, G., Karadzhov, G. E., Xiao, J.
core
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source