Results 171 to 180 of about 543,962 (251)

Tailoring MXene Flake Morphology via Aerosol Jet Printing for Biological and Strain Sensor Applications

open access: yesSmall, EarlyView.
Aerosol Jet Printing (AJP), coupled with a novel in situ monitoring method, enabled the controlled fabrication of aligned and crumpled Ti3C2Tx MXenes for diverse applications. Demonstrated across multiple 2D materials, this scalable strategy stablishes flake morphology as a controllable design parameter for engineering application‐specific material ...
Javier Gutierrez‐Gonzalez   +18 more
wiley   +1 more source

Hardware‐Efficient Locality‐Preserving Graph Processing via Ferroelectric Fowler–Nordheim Tunneling Crossbar Array

open access: yesSmall, EarlyView.
Real‐world graph data are directly mapped onto an mCBA, enabling node similarity to be computed through a single current readout. Strongly nonlinear devices suppress long‐range multi‐hop contributions while preserving local connectivity, whereas weakly nonlinear devices allow excessive signal propagation.
Jae‐Hyun Lee   +7 more
wiley   +1 more source

Sprayable MXene Hydrogels With Composition‐Driven Interfacial Stabilization and on‐Skin Gelation for Conformal Postsurgical Photothermal Therapy

open access: yesSmall, EarlyView.
A sprayable MXene‐loaded thermosensitive hydrogel was developed for postoperative melanoma treatment. Molecular simulations combined with experimental analyses demonstrated that polymer composition regulates MXene oxidation. The optimized hydrogel effectively preserved photothermal performance under physiological conditions, enabling efficient near ...
Taek Hwang   +15 more
wiley   +1 more source

Pyrene‐linked heterocyclic pyrazoles: Synthesis, antimicrobial screening, and in silico molecular insights

open access: yesSmart Molecules, EarlyView.
A series of novel pyrene‐linked heterocyclic pyrazoles were synthesized and structurally characterized. The compounds were evaluated for antimicrobial activity against selected bacterial and fungal strains, showing promising inhibitory effects. Molecular docking studies provided insights into binding interactions and structure–activity relationships ...
Dinkal V. Kasundra, Paresh N. Patel
wiley   +1 more source

Design, synthesis and activity evaluation of tetrahydroisoquinoline‐based programmed cell death ligand 1 inhibitors

open access: yesSmart Molecules, EarlyView.
Based on a 3D‐quantitative structure‐activity relationship pharmacophore model, structural optimization of Y6 yielded Y7f. Mechanistic studies revealed that Y7f acted as a programmed death receptor 1/programmed cell death ligand 1 (PD‐L1) interaction inhibitor by inducing PD‐L1 dimerization. Y7f restored T‐cell function.
Menglin Yu   +15 more
wiley   +1 more source

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