Results 31 to 40 of about 234,335 (333)

Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation

FEBS Letters, EarlyView.
The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen, Zenon Toprakcioglu, Michele Vendruscolo   +2 more
wiley   +1 more source

C9orf72 ALS‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules

FEBS Letters, EarlyView.
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican, Yara Nabawi, William Hongyu Zhang, Dunja Petrovic, Markus Wehrmann, Sara Muñoz‐García, Seda Koyuncu, David Vilchez   +7 more
wiley   +1 more source

Low-Cost System with Transient Reduction for Automatic Power Factor Controller in Three-Phase Low-Voltage Installations

Energies
In power engineering, the importance of maintaining a high power factor in low-voltage electrical installations is known. In power substations for industry, the usual method of coupling is to use an automatic power factor controller which connects ...
Gabriel Nicolae Popa, Corina Maria Diniș   +1 more
doaj   +1 more source

Designing functional ferroelectric interfaces from first-principles: dipoles and band bending at oxide heterojunctions

New Journal of Physics, 2019
The fundamental phenomena at ferroelectric interfaces have been the subject of thorough theoretical and computational studies due to their usefulness in a large variety of emergent electronic devices, solar cells and catalysts.
Rusu Dorin, Lucian Dragos Filip, Lucian Pintilie, Keith Tobias Butler, Neculai Plugaru   +4 more
doaj   +1 more source

Recent progress on dielectric polymers and composites for capacitive energy storage

iEnergy, 2022
Polymer dielectrics-based capacitors are indispensable to the development of increasingly complex, miniaturized and sustainable electronics and electrical systems.
Zhubing Han, Qing Wang
doaj   +1 more source

Nonlinear Performance of BAW Filters Including BST Capacitors [PDF]

, 2014
This paper evaluates the nonlinear effects occurring in a bulk acoustic wave (BAW) filter which includes barium strontium titanate (BST) capacitors to cancel the electrostatic capacitance of the BAW resonators.
Billard, C., Collado, C., David, J.-B., Hueltes, A., Mateu, J., Reinhardt, A., Rocas, E., Verdu, J.   +7 more
core   +1 more source

Effects of Surface Transition and Adsorption on Ionic Liquid Capacitors [PDF]

, 2020
Room-temperature ionic liquids (RTILs) are synthetic electrolytes with electrochemical stability superior to that of conventional aqueous-based electrolytes, allowing a significantly enlarged electrochemical window for application as capacitors.
Chao, Huikuan, Wang, Zhen-Gang
core  

An efficient strategy for producing RNA‐free Nucleocapsid protein of SARS‐CoV‐2 for biochemical and structural investigations

FEBS Open Bio, EarlyView.
Cleavable N‐terminal Thioredoxin fusion enabled soluble expression and purification of otherwise insoluble SARS‐CoV‐2 Nucleocapsid (N) protein. A four‐step purification strategy yielded highly homogeneous, RNA‐free N protein. Binding assays showed high RNA affinity (Kd ~ 28 nm). The study will facilitate high‐resolution structural studies of N protein,
Shweta Singh, Gagan D. Gupta
wiley   +1 more source

Capacitance–Voltage Fluctuation of Si_xN_y-Based Metal–Insulator–Metal Capacitor Due to Silane Surface Treatment

Micromachines
In this study, we analyze metal–insulator–metal (MIM) capacitors with different thicknesses of SixNy film (650 Å, 500 Å, and 400 Å) and varying levels of film quality to improve their capacitance density.
Tae-Min Choi, Eun-Su Jung, Jin-Uk Yoo, Hwa-Rim Lee, Sung-Gyu Pyo   +4 more
doaj   +1 more source

Ro 31‐8220 suppresses bladder cancer progression via enhancing autophagy in vitro and in vivo

FEBS Open Bio, EarlyView.
The pan‐protein kinase C inhibitor Ro‐31‐8220 demonstrates potent anti‐bladder cancer effects both in vitro and in vivo by suppressing migration/invasion, inducing apoptosis and crucially activating autophagy, where blocking autophagy with chloroquine reduces its cell‐killing efficacy, suggesting its promise as a novel therapeutic candidate requiring ...
Shengjun Fu, Yan Tao, Shan Wu, Yuwen Gong, Youli Zhao, Shaomin Niu, Hui Cheng, You Mu, Na Xu, Ying Wang, Jianzhong Lu, Shanhui Liu, Lanlan Li   +12 more
wiley   +1 more source