Results 71 to 80 of about 180,619 (295)

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz, Christopher H. Thompson, Linda C. Laux, Alfred L. George Jr.   +3 more
wiley   +1 more source

Substituted Bi3.5Mg1.8Nb2.7O13.8 pyrochlores with transition metals (Zn, Ni and Cd): Doping mechanism, structure and electrical properties [PDF]

Processing and Application of Ceramics
The influence of transition metals (Zn, Cd and Ni) on bismuth magnesium niobate (Bi3.5Mg1.8Nb2.7O13.8, BMN) pyrochlores was investigated. Considering the difference in their ionic radii, Cd was postulated to substitute Mg at the eight-fold coordinated A ...
Tan Phei Yi, Tan Kar Ban, Khaw Chwin Chieh, Ananda Murthy H.C., Balachandran Ruthramurthy, Chen Soo Kien, Lee Jew Oon, Chan Kah Yoong, Lu Ming   +8 more
doaj   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

An Overview of Inertia Emulation Strategies for DC Microgrids: Stability Analysis and AC Microgrid Analogies

IEEE Open Journal of the Industrial Electronics Society
Inertia is a critical factor in maintaining the frequency stability of power systems. However, the growing integration of power electronics-based renewable energy sources (RESs) has significantly reduced system inertia.
Mahdis Haddadi, Saman A. Gorji, Samson S. Yu   +2 more
doaj   +1 more source

Electrical Characterization of PbZr0.4Ti0.6O3 Capacitors

, 2006
We have conducted a careful study of current-voltage (I-V) characteristics in fully integrated commercial PbZr0.4Ti0.6O3 thin film capacitors with Pt bottom and Ir/IrO2 top electrodes.
Baniecki, D. J. Jung, Haun, Hu, J. F. Scott, Meyer, P. Zubko, Smyth, Zubko   +8 more
core   +1 more source

On the persistence of polar domains in ultrathin ferroelectric capacitors [PDF]

, 2017
The instability of ferroelectric ordering in ultra-thin films is one of the most important fundamental issues pertaining realization of a number of electronic devices with enhanced functionality, such as ferroelectric and multiferroic tunnel junctions or
Bark, Chung-Wung, Catalan, Gustau, Eom, Chang-Beom, Gruverman, Alexei, Lu, Haidong, Martí, Xavi, Santiso, José, Zubko, Pavlo   +7 more
core   +4 more sources

A Robust Adaptive One‐Sample‐Ahead Preview Super‐Twisting Sliding Mode Controller

International Journal of Adaptive Control and Signal Processing, EarlyView.
Block Diagram of the Robust Adaptive One‐Sample‐Ahead Preview Super‐Twisting Sliding Mode Controller. ABSTRACT This article introduces a discrete‐time robust adaptive one‐sample‐ahead preview super‐twisting sliding mode controller. A stability analysis of the controller by Lyapunov criteria is developed to demonstrate its robustness in handling both ...
Guilherme Vieira Hollweg, Paulo Jefferson Dias de Oliveira Evald, Shivam Chaturvedi, Hilton Abilio Gründling, Rodrigo Varella Tambara, Wencong Su   +5 more
wiley   +1 more source

Investigation of Tantalum Wet Slug Capacitor Failures in the Apollo Telescope Mount Charger Battery Regulator Modules [PDF]

This investigation describes the capacitor failures and to identify the cause of the failure mechanism. Early failures were thought to have happened because of age and/or abuse since the failed capacitors were dated 1967.
Wiedeman, D. H., Williams, J. F.
core   +1 more source

Charging damage in floating metal-insulator-metal capacitors [PDF]

, 2002
In this paper, charging induced damage (CID) to metal-insulator-metal capacitors (MIMC) is reported. The damage is caused by the build up of a voltage potential difference between the two plates of the capacitor.
Ackaert, Jan, Coppens, P., De Backer, E., Wang, Zhichun   +3 more
core   +2 more sources

Characterization of Defect Distribution in an Additively Manufactured AlSi10Mg as a Function of Processing Parameters and Correlations with Extreme Value Statistics

Advanced Engineering Materials, EarlyView.
Predicting extreme defects in additive manufacturing remains a key challenge limiting its structural reliability. This study proposes a statistical framework that integrates Extreme Value Theory with advanced process indicators to explore defect–process relationships and improve the estimation of critical defect sizes. The approach provides a basis for
Muhammad Muteeb Butt, Varma Kvvssn, Hossein Laieghi, Zia Uddin, Peyman Ansari, E. Kıvanç Sadak, Can Barış Toprak, Hüseyin Kızıl, Enrico Salvati   +8 more
wiley   +1 more source