Results 101 to 110 of about 10,079,690 (327)

Data for 'Global trends in grassland carrying capacity and relative stocking density of livestock'

open access: green, 2022
Johannes Piipponen   +7 more
openalex   +1 more source

Capacity Building and Resilience [PDF]

open access: yes, 2014
This report from Arts Midwest, investigates how small and mid-sized arts organizations learn, adapt, and grow. Examining the experiences of eight organizations participating in this leadership and strategy development program, this report identifies four
M. Christine Dwyer, Sarah Lutman
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

(P1-16) Local Health-Related Capacities in the Northern Haiti Post-Earthquake Response [PDF]

open access: bronze, 2011
Robert King   +6 more
openalex   +1 more source

Foundations Need Capacity, Too: Initial Findings from the Foundation Core Capacity Assessment Tool [PDF]

open access: yes, 2016
For many years, the social sector has paid substantial attention to the issue of nonprofit effectiveness. By contrast, comparatively little attention has been paid to the capacities that foundations themselves need to achieve impact.
Deepti Sood, Jared Raynor, Melinda Fine
core  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

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