Results 71 to 80 of about 12,966,863 (379)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Exerting Capacity.

open access: yesWestern journal of nursing research, 2017
Patient safety has been at the forefront of nursing research since the release of the Institute of Medicine's report estimating the number of preventable adverse events in hospital settings; yet no research to date has incorporated the perspectives of bedside nurses using classical grounded theory (CGT) methodology.
J. Michael Leger, Carolyn A. Phillips
openaire   +2 more sources

Imbrication de la mise en oeuvre concertée et solidaire du Traité sur les ressources phytogénétiques et du Protocole de Nagoya dans le conexte d’objetifs de politiques nationales plus larges: un atelier destine à des équipes nationales d’acteurs de politiques [PDF]

open access: yes, 2019
This report provides highlights from a workshop entitled “Embedding mutually supportive implementation of the Plant Treaty and the Nagoya Protocol in the context of broader national policy goals. A workshop for national teams of policy actors”.
ABS Capacity Development Initiative   +1 more
core  

Hybrid Zero-capacity Channels

open access: yes, 2012
There are only two known kinds of zero-capacity channels. The first kind produces entangled states that have positive partial transpose, and the second one - states that are cloneable.
Oppenheim, Jonathan, Strelchuk, Sergii
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Dynamic Characteristics of Suspended Load and Bed Load Transport in Meltwater Runoff of Qiyi Glacier

open access: yesShuitu Baochi Xuebao
[Objective] The transportation of sediment via glacial meltwater can not only reflect the glacial erosion and landform evolution, but also is one of the important sediment sources for the downstream river.
ZHAO Yi   +5 more
doaj   +1 more source

Big Neural Networks Waste Capacity [PDF]

open access: yes, 2013
This article exposes the failure of some big neural networks to leverage added capacity to reduce underfitting. Past research suggest diminishing returns when increasing the size of neural networks.
Bengio, Yoshua, Dauphin, Yann N.
core  

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

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