Results 51 to 60 of about 2,918,690 (278)
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
BMC MedicineBackground Marburg virus disease (MVD) is a highly fatal hemorrhagic fever with fatality rates between 33 and 88% in sub-Saharan Africa. Rwanda reported its first MVD outbreak on September 27, 2024.
Gashaija Absolomon +14 more
doaj +1 more source
Measuring Impact: Advocacy Evaluation & Capacity Building [PDF]
, 2012 Developing up-front organizational advocacy capacity is important in the evaluation process. An organization should first assess its staff, knowledge, coalition partners and other resources to determine what may be needed for their upcoming advocacy ...
Sue Hoechstetter
core
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
BMC Primary CareBackground Digital health platforms are transforming primary care delivery in low- and middle-income countries. Babyl provided Rwanda’s first nationwide telemedicine service from 2019 to September 2023, integrating nurse-led triage with physician ...
Felix K. Rubuga +11 more
doaj +1 more source
Building Advocacy Capacity: Where Grantees Started [PDF]
, 2009 Describes the baseline levels of core advocacy capacities of groups participating in Consumer Voices for Coverage, a twelve-state initiative to build consumer organizations' network and advocacy capacity.
Debra A. Strong +3 more
core
Capacity-building in open education: an Australian approach [PDF]
, 2015 Addressing the gap between global open educational resource (OER) proliferation and the slow adoption of OER and open educational practices (OEP) in Australian higher education, this paper focuses on a capacity-building project targeting academics ...
Bossu, Carina, Fountain, WG
core +3 more sources
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Sociedad y Ambiente, 2019 El objetivo del artículo es identificar y analizar el papel de la Visión Africana del Agua 2025 (VAA2025) en torno al acceso al agua para consumo humano en Mali, África.
Halimatou Coulibaly +1 more
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source