Results 71 to 80 of about 5,731,628 (253)

Capacity building and community development

, 2010
This chapter is about the language of capacity building. Language is important in that it powerfully, but often unconsciously, shapes the way we understand the concepts we are using. It reveals the assumptions, often implicit rather than explicit, behind
Ife, Jim (R18858), Jim Ife
core   +1 more source

Africa Capacity Report 2014: Capacity Imperatives for Regional Integration in Africa

, 2014
The Africa Capacity Report (ACR) and its supporting indicators offer inputs for decisions on what to finance to develop capacity. Most countries are doing well on their policy environments and having processes in place to implement policies.
African Capacity Building Foundation (19289548)
core   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Criminal Law (Amendment) Act, 2013: Will it ensure women’s safety in public spaces?

Space and Culture, India, 2013
The horrific gang-rape and the subsequent murder of Nirbyaya (fearless) in December 2012, impelled the Government of India to pass the Criminal Law (Amendment) Act, 2013. The key aim of this article is to review this Act in the light of women's safety in
Rituparna Bhattacharyya
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Simulating the Worst to Prepare the Best: A study of humanitarian simulations and their benefits [PDF]

, 2013
Simulations are being used widely across the humanitarian sector, in a variety of contexts and involve numerous stakeholders. The sector is placing increasing value on simulations as important staff capacity, preparedness and relationship building ...
Staples, James, Barnhardt, Daniel, Sitko, Pamela, Bulten, Odile, Hockaday, David   +4 more
core   +1 more source

Blood glucose outcomes of anti-retroviral therapy naïve Ugandan people with HIV with pre-diabetes mellitus initiated on dolutegravir for 48 weeks

BMC Infectious Diseases
Background The Uganda ministry of Health recommends frequent blood glucose monitoring for the first six months on dolutegravir, in people with HIV (PWH) having pre-diabetes mellitus (pre-DM). We sought to determine if indeed PWH with pre-diabetes started
Frank Mulindwa, Jean-Marc Schwarz, Nele Brusselaers, Martin Nabwana, Robert Bollinger, Allan Buzibye, Willington Amutuhaire, George Yendewa, Eva Laker Agnes Odongpiny, Ronald Kiguba, Barbara Castelnuovo   +10 more
doaj   +1 more source

Phytochemical Characterization and Antioxidant, Antimicrobial, and Poultry Meat Preservation Potential of Ziziphus mauritiana

Foods
Consumer preference for clean-label products is driving interest in natural antioxidants and antimicrobials that can replace synthetic preservatives. Ziziphus mauritiana (sidr), a resilient desert tree native to the arid Gulf region, has being tested as ...
Mohamed Gamal Shehata, Hassan Mohamed Al Marzooqi, Hanan Sobhy Afifi, Saad H. D. Masry   +3 more
doaj   +1 more source