Results 71 to 80 of about 583,418 (306)
Simulating the Worst to Prepare the Best: A study of humanitarian simulations and their benefits [PDF]
, 2013 Simulations are being used widely across the humanitarian sector, in a variety of contexts and involve numerous stakeholders. The sector is placing increasing value on simulations as important staff capacity, preparedness and relationship building ...
Staples, James +4 more
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BMC Health Services Research, 2018 Background To evaluate the performance of a novel triage system for Transient Ischemic Attack (TIA) units built upon an existent clinical prediction rule (CPR) to reduce time to unit arrival, relative to the time of symptom onset, for true TIA and minor ...
Maximilian B. Bibok +8 more
doaj +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Capacity building assistance (CBA) glossary [PDF]
The Capacity Building Assistance (CBA) Glossary has been developed by the Capacity Building Assistance Provider Network (CPN) in partnership with the Capacity Building Branch (CBB), in the Division of HIV/AIDS Prevention (DHAP) at the Centers for Disease
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Roma Organisations: Capacity building [PDF]
, 2008 Capacity-building work with the poorest community in Europe, the Roma, has enhanced advocacy, lobbying and negotiating skills that have led to improved interaction with local authorities on education and ...
Judeh, Reem
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Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Playing With Reality: Emergency Capacity Building Project simulations case study
, 2012 This Emergency Capacity Building (ECB) Project simulation case study focuses on the lessons learnt from implementing the ECB Project multi-agency simulations at the national level between April 2010 and March 2012, using the ECB Simulations ...
Lumsdon, Sarah, Hockaday, David
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Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
, 2020 This entry provides first an overview of the main characteristics of the concept and a short historical overview. Subsequent sections present profiles for the different approaches developed over time, with particular focus on administrative capacity building.
openaire +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source