Results 61 to 70 of about 5,731,628 (253)
BMC Health Services ResearchBackground Despite the high demand for public services globally, ensuring the quality of services provided by public health facilities is challenging.
Kizito Kayumba +14 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Building Capacity for Domestic Resource Mobilization: The Role of the Civil Society
, 2016 The policy brief by the African Capacity Building Foundation (ACBF) highlights that while it is widely agreed that domestic resource mobilization is the way to go, the 2015 Africa Capacity Report shows that this may not be achieved because of one missing
African Capacity Building Foundation (19289548)
core +1 more source
Emergency Simulations: Administrator's guide [PDF]
, 2007 By simulating a disaster humanitarian staff can practice responding to an emergency and collaborating with diverse colleagues in an intense emergency context. The Emergency Capacity Building Project produced this guide to coordinating both
Klenk, Jeff
core +1 more source
Sociedad y Ambiente, 2019 El objetivo del artículo es identificar y analizar el papel de la Visión Africana del Agua 2025 (VAA2025) en torno al acceso al agua para consumo humano en Mali, África.
Halimatou Coulibaly +1 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Capacity building assistance (CBA) glossary [PDF]
The Capacity Building Assistance (CBA) Glossary has been developed by the Capacity Building Assistance Provider Network (CPN) in partnership with the Capacity Building Branch (CBB), in the Division of HIV/AIDS Prevention (DHAP) at the Centers for Disease
core
BMC Health Services Research, 2018 Background To evaluate the performance of a novel triage system for Transient Ischemic Attack (TIA) units built upon an existent clinical prediction rule (CPR) to reduce time to unit arrival, relative to the time of symptom onset, for true TIA and minor ...
Maximilian B. Bibok +8 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source