Results 31 to 40 of about 481 (129)
ABSTRACT A 16‐year‐old girl presenting with calcinosis cutis and localized scleroderma subsequently developed delayed‐onset idiopathic inflammatory myopathy five years after initial skin involvement. Despite the absence of typical dermatomyositis features and negative myositis‐specific antibodies, whole‐body MRI revealed extensive subclinical muscle ...
Edoardo Marrani +5 more
wiley +1 more source
Nailfold capillaroscopy has been shown to reflect microvascular disturbances mainly in connective tissue diseases, and the development of video capillaroscopy made it possible to determine capillary red blood cell velocity by measuring the displacement ...
Masao WATANABE +5 more
doaj +1 more source
BackgroundThe cutaneous microangiopathy plays a key role in the development of the skin clinical lesions of venous insufficiency. Capillaroscopy allows a non-invasive observation of the superficial skin capillaries of the lower leg, which have previously
Patrick H. Carpentier +6 more
doaj +1 more source
Quantitative T2* Magnetic Resonance Imaging for Iron Detection in Soft Tissue of the Fingers
T2* MRI was evaluated for detecting iron in soft tissues of the fingers. After visual inspection of dual‐colored maps, multiple regions of interest were placed in the soft tissues at areas that indicated increased susceptibility. Lower T2* values, indicative of iron deposition, were detected in patients with microvasculopathy (right panel) but not in ...
Artemis Galani +6 more
wiley +1 more source
Assessing the Health and Functionality of the Microcirculation Using Thermal Imaging
We review the techniques of thermal imaging for assessing the functional consequences of lowered blood flow in the microcirculation that accompanies many chronic, inflammatory diseases. A comparison is made with laser Doppler/speckle methods. ABSTRACT The microcirculation, composed of vessels below 100 μm in diameter, sustains tissue perfusion and ...
Douglas B. Kell, Etheresia Pretorius
wiley +1 more source
Nailfold capillaroscopy in myositis: A case series
Nailfold capillaroscopy is well established in systemic sclerosis; however, abnormalities (scleroderma or scleroderma-like patterns) are identified in other connective tissue diseases, such as myositis, even in the absence of Raynaud’s phenomenon ...
Thaisa Cotton +4 more
doaj +1 more source
Clinical Associations of Anti‐RNPC3 Autoantibodies in Mixed Connective Tissue Disease
Objective The RNA‐binding region‐containing protein 3 (RNPC3) protein acts as a molecular bridge, promoting U11/U12 RNP complex formation. In previous reports, patients with systemic sclerosis (SSc) with anti‐RNPC3 autoantibodies had an increased risk of interstitial lung disease (ILD), severe gastrointestinal (GI) disease, and cancer.
Darya S. Jalaledin +14 more
wiley +1 more source
OBJETIVO: Estudar a associação entre alterações capilaroscópicas e lesões em órgãos-alvo na esclerose sistêmica (ES). MÉTODOS: Noventa e um pacientes com ES foram avaliados através de entrevista, exame físico, capilaroscopia periungueal (CPU), sorologia,
Markus Bredemeier +9 more
doaj +1 more source
Capillaroscopy and Immunological Profile in Systemic Sclerosis
Introduction: Data on the associations between capillaroscopic changes and diagnostic systemic-sclerosis (SSc)-related antibodies are scarce. Presence of such correlation would improve current knowledge about the disease’s pathogenesis by revealing the ...
Sevdalina Nikolova Lambova +5 more
doaj +1 more source
Objective To characterize clinical and transcriptomic differences in juvenile scleromyositis overlap (jOverlap) compared to juvenile systemic sclerosis (jSSc) and juvenile dermatomyositis (JDM), focusing on autoantibody profiles, organ involvement, treatment, and peripheral blood gene expression.
Amanda D. Robinson +6 more
wiley +1 more source

