Results 31 to 40 of about 481 (129)

Calcinosis Cutis and Delayed‐Onset Myositis in a Case of Suspected Localized Scleroderma: A Diagnostic and Therapeutic Challenge

open access: yesPediatric Dermatology, EarlyView.
ABSTRACT A 16‐year‐old girl presenting with calcinosis cutis and localized scleroderma subsequently developed delayed‐onset idiopathic inflammatory myopathy five years after initial skin involvement. Despite the absence of typical dermatomyositis features and negative myositis‐specific antibodies, whole‐body MRI revealed extensive subclinical muscle ...
Edoardo Marrani   +5 more
wiley   +1 more source

High Speed Digital Video Capillaroscopy: Nailfold Capillary Shape Analysis and Red Blood Cell Velocity Measurement

open access: yesJournal of Biomechanical Science and Engineering, 2007
Nailfold capillaroscopy has been shown to reflect microvascular disturbances mainly in connective tissue diseases, and the development of video capillaroscopy made it possible to determine capillary red blood cell velocity by measuring the displacement ...
Masao WATANABE   +5 more
doaj   +1 more source

Video-capillaroscopy, a promising tool for the clinical evaluation of patients with chronic venous insufficiency

open access: yesFrontiers in Medicine, 2023
BackgroundThe cutaneous microangiopathy plays a key role in the development of the skin clinical lesions of venous insufficiency. Capillaroscopy allows a non-invasive observation of the superficial skin capillaries of the lower leg, which have previously
Patrick H. Carpentier   +6 more
doaj   +1 more source

Quantitative T2* Magnetic Resonance Imaging for Iron Detection in Soft Tissue of the Fingers

open access: yesNMR in Biomedicine, Volume 39, Issue 6, June 2026.
T2* MRI was evaluated for detecting iron in soft tissues of the fingers. After visual inspection of dual‐colored maps, multiple regions of interest were placed in the soft tissues at areas that indicated increased susceptibility. Lower T2* values, indicative of iron deposition, were detected in patients with microvasculopathy (right panel) but not in ...
Artemis Galani   +6 more
wiley   +1 more source

Assessing the Health and Functionality of the Microcirculation Using Thermal Imaging

open access: yesJournal of Biophotonics, Volume 19, Issue 5, May 2026.
We review the techniques of thermal imaging for assessing the functional consequences of lowered blood flow in the microcirculation that accompanies many chronic, inflammatory diseases. A comparison is made with laser Doppler/speckle methods. ABSTRACT The microcirculation, composed of vessels below 100 μm in diameter, sustains tissue perfusion and ...
Douglas B. Kell, Etheresia Pretorius
wiley   +1 more source

Nailfold capillaroscopy in myositis: A case series

open access: yesSAGE Open Medical Case Reports
Nailfold capillaroscopy is well established in systemic sclerosis; however, abnormalities (scleroderma or scleroderma-like patterns) are identified in other connective tissue diseases, such as myositis, even in the absence of Raynaud’s phenomenon ...
Thaisa Cotton   +4 more
doaj   +1 more source

Clinical Associations of Anti‐RNPC3 Autoantibodies in Mixed Connective Tissue Disease

open access: yesACR Open Rheumatology, Volume 8, Issue 4, April 2026.
Objective The RNA‐binding region‐containing protein 3 (RNPC3) protein acts as a molecular bridge, promoting U11/U12 RNP complex formation. In previous reports, patients with systemic sclerosis (SSc) with anti‐RNPC3 autoantibodies had an increased risk of interstitial lung disease (ILD), severe gastrointestinal (GI) disease, and cancer.
Darya S. Jalaledin   +14 more
wiley   +1 more source

Capilaroscopia periungueal pode sugerir atividade de doença pulmonar na esclerose sistêmica Nailfold capillaroscopy can predict active pulmonary involvement in systemic sclerosis

open access: yesRevista Brasileira de Reumatologia, 2004
OBJETIVO: Estudar a associação entre alterações capilaroscópicas e lesões em órgãos-alvo na esclerose sistêmica (ES). MÉTODOS: Noventa e um pacientes com ES foram avaliados através de entrevista, exame físico, capilaroscopia periungueal (CPU), sorologia,
Markus Bredemeier   +9 more
doaj   +1 more source

Capillaroscopy and Immunological Profile in Systemic Sclerosis

open access: yesLife, 2022
Introduction: Data on the associations between capillaroscopic changes and diagnostic systemic-sclerosis (SSc)-related antibodies are scarce. Presence of such correlation would improve current knowledge about the disease’s pathogenesis by revealing the ...
Sevdalina Nikolova Lambova   +5 more
doaj   +1 more source

Distinct by Design: Unraveling the Unique Clinical and Transcriptomic Identity of Juvenile Scleromyositis Overlap Compared to Juvenile Systemic Sclerosis and Juvenile Dermatomyositis: Implications for Care and Pathogenesis

open access: yesACR Open Rheumatology, Volume 8, Issue 3, March 2026.
Objective To characterize clinical and transcriptomic differences in juvenile scleromyositis overlap (jOverlap) compared to juvenile systemic sclerosis (jSSc) and juvenile dermatomyositis (JDM), focusing on autoantibody profiles, organ involvement, treatment, and peripheral blood gene expression.
Amanda D. Robinson   +6 more
wiley   +1 more source

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