Results 51 to 60 of about 481 (129)

Analysis of the Dynamics of Clinical Parameters and Serum Angiogenic Factors in Systemic Sclerosis Patients Undergoing Tocilizumab Treatment

Experimental Dermatology, Volume 35, Issue 2, February 2026.
This study demonstrates that tocilizumab (TCZ) treatment promotes microvascular recovery in systemic sclerosis (SSc), as evidenced by increased capillary density and that this improvement in vasculopathy is closely associated with enhanced pulmonary function.
Yuichiro Segawa, Takehiro Takahashi, Takuya Takahashi, Kenta Oka, Yumi Kambayashi, Toshiya Takahashi, Yoshihide Asano   +6 more
wiley   +1 more source

Does Microvascular Function Play a Role in the Etiology of Bell’s Palsy?

Haseki Tıp Bülteni, 2020
Aim:The aim of our study was to investigate whether systemic microvascular function affects the development and prognosis of Bell’s palsy (BP) or not.Methods:Sixty patients, who were admitted to our hospital between June 2017 and May 2018 and diagnosed ...
Arzu Karaman Koç, Hasan Emre Koçak, Bilgen Çakıl Erdoğan, Hüseyin Avni Ulusoy, Mehmet Yiğitbay, Harun Acıpayam, Kamil Hakan Kaya   +6 more
doaj   +1 more source

Rethinking Strategies for a Pharmaceutical Approach to Pain Related to Connective Tissue–Related Raynaud Phenomenon in the United States

Arthritis Care &Research, Volume 78, Issue 1, Page 106-112, January 2026.
Objective There are no US Food and Drug Administration–approved therapies for Raynaud phenomenon (RP) in the United States. Clinical trials have been challenged by study design. Important advances in RP patient‐reported outcome measures and mechanistic quantification allow RP‐related pain characterization.
Tracy M. Frech, Charles G. Frech, W. David Merryman, Andrew Sternlicht, Justin Baba   +4 more
wiley   +1 more source

Dermatoscopic Characteristics, Lesional Capillaroscopic Features, and Histopathological Correlation of Small Plaque Parapsoriasis and Mycosis Fungoides

Dermatology Practical & Conceptual
Introduction: Dermatoscopy is a frequently used non-invasive diagnostic procedure. Objectives: Considering that mycosis fungoides (MF) mimics parapsoriasis clinically in  early stages, we aim to determine the dermatoscopic criteria and the ...
Dilara İlhan Erdil, Merve Cin, Duygu Erdil, Vildan Manav, Buğra Burç Dağtaş, Ayşe Esra Koku Aksu   +5 more
doaj   +1 more source

Anti‐Eukaryotic Initiation Factor 2B‐Positive Systemic Sclerosis‐Associated Interstitial Lung Disease With Progressive Fibrosis: A Case Report

Respirology Case Reports, Volume 14, Issue 1, January 2026.
We report the case of a patient with anti‐eIF2B‐positive SSc‐ILD managed with stepwise mycophenolate titration and subsequent nintedanib addition, accompanied by serial biomarkers and clinical follow‐up to help delineate the therapeutic course within this rare serological phenotype.
Hiro Ikeda, Ryo Tachikawa, Tsuyoshi Sasada, Shuji Sumitomo   +3 more
wiley   +1 more source

Gender-Related Difference in Skin Oxygenation in Young Patients with Uncomplicated Type 1 Diabetes

Biomedicines
Gender, through genetic, epigenetic and hormonal regulation, is an important modifier of the physiological mechanisms and clinical course of diseases. In diabetes mellitus, there are gender differences in incidence, prevalence, morbidity, and mortality ...
Jolanta Neubauer-Geryk, Małgorzata Myśliwiec, Leszek Bieniaszewski   +2 more
doaj   +1 more source

Assessing nailfold microvascular structure with ultra-wideband raster-scan optoacoustic mesoscopy

Photoacoustics, 2018
Nailfold capillaroscopy, based on bright-field microscopy, is widely used to diagnose systemic sclerosis (SSc). However it cannot reveal information about venules and arterioles lying deep under the nailfold, nor can it provide detailed data about ...
J. Aguirre, B. Hindelang, Andrei Berezhnoi, U. Darsow, F. Lauffer, K. Eyerich, T. Biedermann, V. Ntziachristos   +7 more
doaj   +1 more source

A matter arising: When should inflammatory and autoimmune rheumatic diseases be considered ‘early’?

European Journal of Clinical Investigation, Volume 56, Issue 1, January 2026.
Timely recognition of inflammatory and autoimmune rheumatic diseases (IARDs) is important to optimize the early diagnosis with tailored interventions and possible prevention of irreversible organ damage. This narrative review provides an update by summarizing the advances in identifying the early stages of rheumatoid arthritis, systemic sclerosis and ...
Elvis Hysa, Emanuele Gotelli, Carmen Pizzorni, Sabrina Paolino, Alberto Sulli, Vanessa Smith, Rosanna Campitiello, Maurizio Cutolo   +7 more
wiley   +1 more source

Association of nailfold capillaroscopic features with cardiac block and arrhythmias due to systemic sclerosis-related primary heart involvement

Rheumatology
Objectives Impaired microvascular function has been implicated as a complication affecting multi­ple organs in systemic sclerosis (SSc). We investigated the correlation between microvascular damage on nailfold video capillaroscopy (NVC) and cardiac ...
Maryam Salimi-Beni, Leila Azizi, Maryam Mohebi, Negin Mohtasham, Ali Kabir, Hadi Poormoghim   +5 more
doaj   +1 more source

Potentialities of Digital Capillaroscopy in the Diagnostics of Oedema Syndrome

Journal of Biomedical Photonics & Engineering, 2017
The paper is devoted to the study of digital capillaroscopy potentialities in the assessment of oedema syndrome by the example of a group of patients with diseases of cardiovascular system (CVS).
Yury I. Gurfinkel, Maria L. Sasonko
doaj   +1 more source