Results 91 to 100 of about 450,994 (299)

Applications of capillary electrophoresis to the analysis of compounds of clinical, forensic, cosmetological, environmental, nutritional and pharmaceutical importance

Journal of the Brazilian Chemical Society, 2003
Since its inception in the 80's, capillary electrophoresis has matured into a well-established separation technique, actually encompassing a family of electrodriven techniques with distinct separation mechanisms and selectivity, performed in a single ...
Tavares Marina F. M., Jager Alessandra V., Silva Clóvis L. da, Moraes Edgar P., Pereira Elisabete A., Lima Elizabete C. de, Fonseca Fabiana N., Tonin Fernando G., Micke Gustavo A., Santos Márcia R., Oliveira Marcone A. L. de, Moraes Maria de Lourdes L. de, Kampen Maria Helena van, Fujiya Neide M.   +13 more
doaj  

Quantitative sample injection for capillary electrophoresis

, 2003
An apparatus including a rotary-type injector was designed for quantitative sample injection in capillary electrophoresis (CE), in which both pressurized flow and electroosmotic flow were used to drive the background electrolyte solution.
Yao, CY, Ruyu Gao, Gao, RY, Yan, C, Chao Yan, Chuanyi Yao   +5 more
core   +1 more source

An Unbiased Geometry‐Resolved Membrane Platform for Proteome‐Scale Discovery of Membrane Curvature Sensors

Advanced Science, EarlyView.
A novel geometry‐resolved membrane platform provides a seamlessly integrated pipeline for studying curvature‐sensing proteins. By linking shotgun proteomics with quantitative imaging, this approach enables both the unbiased discovery and rigorous validation of novel sensors across the entire curvature range—positive, negative, and zero.
Takumi Komikawa, Rikuto Kawakami, Kunanon Chattrairat, Tatsuya Niwa, Taiga Ajiri, Takao Yasui, Masayoshi Tanaka   +6 more
wiley   +1 more source

New analytical challenges in characterization of antibody-drug conjugates

Journal of Chromatography Open
Since 1913, when Paul Ehrlich introduced the concept of “selective toxicity”, new strategies to obtain quality control, quantification of the drug were mandatory. For this reason, the introduction of antibody drug conjugates (ADC) has shown many critical
Erika Maria Ricci, Enrico Dainese, Vincenzo De Laurenzi, Giulio Lovato, Gianluca Sala, Marcello Locatelli, Miryam Perrucci   +6 more
doaj   +1 more source

Statistical modeling of STR capillary electrophoresis signal

BMC Bioinformatics, 2019
Background In order to isolate an individual’s genotype from a sample of biological material, most laboratories use PCR and Capillary Electrophoresis (CE) to construct a genetic profile based on polymorphic loci known as Short Tandem Repeats (STRs).
Slim Karkar, Lauren E. Alfonse, Catherine M. Grgicak, Desmond S. Lun   +3 more
doaj   +1 more source

A Simple, Rapid, and Sensitive Method for Analysis of SYPRO Red Labeled SDS-Protein Complexes by Capillary Electrophoresis with Laser-Induced Fluorescence

, 2010
[[abstract]]We describe a segmental filling method for the analysis of SYPRO Red labeled sodium dodecyl sulfate (SDS)-proteins (SRSPs) by capillary electrophoresis-laser induced fluorescence (CE-LIF) with electroosmotic counterflow of poly(ethylene oxide)
Chiu, T.-C.; Lin, Y.-W.; Huang, C.-C.; Chrambach, A.; Chang, H.-T.
core  

Engineered Transformer Base Editor with Enhanced Editing Efficiency

Advanced Science, EarlyView.
A highly efficient transformer base editor system achieves robust genomic editing in a humanized mouse model. This work establishes a versatile and translatable platform, opening new avenues for precision gene therapy. ABSTRACT Canonical cytosine base editors (CBEs) achieve precise C‐to‐T conversions without inducing DNA double‐strand breaks (DSBs ...
Bowen Chen, Letong Liang, Rui Xu, Tianyi Wang, Hongyan Chen, Daru Lu   +5 more
wiley   +1 more source

Applications of capillary electrophoresis in forensic sciences.

, 1995
Applications of capillary electrophoresis in forensic ...
TURRINA, Stefania, Deyl Z., TAGLIARO, Franco, Smith F. P.   +3 more
core   +1 more source

Interaction between netropsin and double-stranded DNA in capillary zone electrophoresis and affinity capillary electrophoresis

, 2002
Capillary zone electrophoresis (CZE) and affinity capillary electrophoresis (ACE) were applied to study the interaction between netropsin and a 14mer double-stranded DNA (dsDNA).
He, XY, Liang, AY, Li, DZ, Lin, BC
core  

Sex‐ and Time‐Resolved Physiological and Gut Ecosystem Responses to a Food‐Grade Microbiome‐Targeted Intervention in Collegiate Endurance Athletes

Advanced Science, EarlyView.
In collegiate endurance athletes, a 6‐week randomized CPYE intervention yielded time‐ and sex‐dependent shifts in field‐based cardiorespiratory, metabolic, and redox indices, accompanied by changes in gut multi‐omics profiles. An exploratory extension during intensified training generates hypotheses warranting future validation.
Meng Zhang, Le Ge, Kaiyang Liu, Yanrong Liu, Guolin Zhao, Lai‐Yu Kwok, Zheng Sun, Zhihong Sun, Wenyi Zhang   +8 more
wiley   +1 more source