Results 141 to 150 of about 228,053 (289)

Amine‐Triggered Azabenz‐Annulation of Cyclic Secondary Amine‐Functionalized Perylene Diimides for Dual‐Mode Sensing

Chemistry – A European Journal, EarlyView.
Pictet‐Spengler Intermediate of a cyclic secondary amine perylene diimide undergoing amine‐triggered conversion to azabenz‐annulated perylene diimide, inducing a high‐contrast green‐to‐yellow color change along with fluorescence turn‐on, demonstrating intuitive “safe” to “warning” dual‐mode sensing.
Irene E. Park, Alejandro J. Cuellar de Lucio, Gregory C. Welch   +2 more
wiley   +1 more source

Expression of mutant TIE2 p.L914F during mouse development causes embryonic lethality and defects in vascular remodeling

Developmental Dynamics, EarlyView.
Abstract Background Sporadic venous malformation (VM) is associated with the hyperactivating p.L914F mutation in TIE2, a receptor tyrosine kinase essential for vascular development. This mutation is not found in hereditary VM, suggesting incompatibility with life when expressed during early vascular development.
Lindsay J. Bischoff, Sandra Schrenk, Kara Soroko, Chhiring Sherpa, Ashok Arasu, Damien Reynaud, Elisa Boscolo   +6 more
wiley   +1 more source

Fractionation of Milligram Quantities of Gadolinium and Terbium Ions by Annular Free‐Flow Isotachophoresis

ELECTROPHORESIS, EarlyView.
ABSTRACT The fractionation of milligram quantities of gadolinium (Gd) and terbium (Tb) ions is demonstrated using annular free‐flow isotachophoresis (ITP) with ammonium as the leading ion and hydronium as the terminating ion, and α‐hydroxyisobutyric acid (HIBA) and acetate as lanthanide complexing ligands.
Hannah Hallikainen, Xiaofeng Guo, Cornelius Ivory   +2 more
wiley   +1 more source

Capillary Electrophoresis With Amperometric Detection for Neurotransmitter Analysis: Principles, Electrode Materials, Methodologies, and Applications

ELECTROPHORESIS, EarlyView.
This review provides a comprehensive summary of monoamine neurotransmitter analysis by capillary electrophoresis with amperometric detection. Fundamental principles of amperometric detection, electrode positioning strategies, and approaches to high‐voltage decoupling are described, followed by a critical comparison of electrode materials, selection of ...
Petr Kubáň, Jiří Volánek, Nguyen Thi Thu Trang, Tran Dai Lam   +3 more
wiley   +1 more source

Construction of Chronic Kidney Disease Mouse Model Induced by Diets With Different Adenine Content

Food Safety and Health, EarlyView.
By administering a 4 weeks adenine diet to C57BL/6J mice, we identified 0.2% adenine in purified feed as the optimal chronic kidney disease model. This model induces severe renal damage, gut dysbiosis, uremic toxin accumulation, and CKD mineral bone disorder, providing a clinically relevant platform for mechanistic and therapeutic studies.
Wanjun Liao, Jiayao Wang, Yilian Huang, Na Zhang, Xiaodan Shi, Zongcai Tu, Zuohua Xie, Tao Yuan, Hongmei Yin   +8 more
wiley   +1 more source

Improvement of Peak Integration in Capillary Electrophoresis: Reference Data Set No. 1. [PDF]

Electrophoresis
Krompholz M, Blanc T, Lu H, Christensen P, Ginot F, Járvás G, Nguyen TD, Prout A, Riehlman T, Wei B, Hutanu A, Kiessig S, Baumann K, Sänger-van de Griend CE, Wätzig H.   +14 more
europepmc   +1 more source

Genetically Engineered Nanobody–Recombinant Antibody Colloidal Gold Strip for Ultrasensitive Atrazine Detection in Fruits and Vegetables

Food Safety and Health, EarlyView.
A sensitive colloidal gold immunochromatographic assay for atrazine was successfully established using genetically engineered nanobody‐recombinant antibody, which overcame the shortcomings of traditional antigen‐antibody. ABSTRACT Colloidal gold immunochromatography (CG‐ICA) is distinguished by its cost‐effectiveness and rapid detection capabilities ...
Jiayong Bao, Peipei Li, A. M. Abd El‐Aty, Jing Zhao, Lingyuan Xu, Chenxi Guo, Jia Li, Xingmei Lei, Sensen Feng, Yi Liu, Si Chen, Fen Jin, Jing Wang, Lufei Zheng, Zhen Cao, Bruce D. Hammock, Maojun Jin   +16 more
wiley   +1 more source

Intact Proteoform Analysis by Capillary Electrophoresis-Mass Spectrometry. Are We There Yet? [PDF]

Angew Chem Int Ed Engl
Gould N, Wang Q, Agar JN, Brodbelt JS, Chen D, Cupp-Sutton KA, Domínguez-Vega E, Fang F, Fillet M, Fischer MS, Gaspar A, Ge Y, Gou MJ, Greguš M, Gstöttner C, Hamidli N, Helms A, Hossain MA, Juetten KJ, Kelleher NL, Kraus T, Larson EJ, Mellors JS, Nagy C, Neusüß C, Redman EA, Schairer J, Wu S, Xu T, Zhao Z, Zhu G, Ivanov AR, Jooß K, Sun L.   +33 more
europepmc   +1 more source

Quantifying Biomolecular Interactions in High-Conductivity Samples With Capillary Electrophoresis. [PDF]

J Sep Sci
De Silva M, Aruna S, Samarakoon B, Whelan RJ.   +3 more
europepmc   +1 more source

Sizing and concentration analysis of cfDNA using Biabooster technology: Results from a prospective plasma‐based collection of 77 patients with locally advanced unresectable esophageal cancer

International Journal of Cancer, EarlyView.
What's New? This study introduces a novel approach for detecting locally advanced esophageal carcinoma using cell‐free DNA (cfDNA) analysis through a highly sensitive fragmentome assay. Unlike traditional sequencing‐based methods that are limited by the absence of specific mutations in esophageal tumors, our method offers an alternative by quantifying ...
Anouchka Modesto, Sophie Gibert, Caroline Delmas, David Tougeron, Amaury Paumier, Alexandre Taillez, Samuel Le Sourd, Delphine Argo Leignel, Philippe Ronchin, Ariane Darut Jouve, Véronique Vendrely, Olivier Riou, Jérôme Martin‐Babau, Thomas Leroy, Laurent Quéro, Naïma Hanoun, Pierre Cordelier, Veronica Pezzella, Jean Pierre Delord, Rosine Guimbaud, Elizabeth Moyal, Catherine Seva   +21 more
wiley   +1 more source