Results 131 to 140 of about 450,994 (299)

The VCPIP1‐UBE3A Deubiquitination‐Ubiquitination Cascade Contributes to Castration‐Resistant Prostate Cancer Progression

Advanced Science, EarlyView.
VCIPIP1 emerges as a molecular link between protein stability and prostate cancer progression. By deubiquitinating and stabilizing UBE3A, VCIPIP1 promotes p53 degradation and progression to castration‐resistant prostate cancer. Elevated VCIPIP1 expression is associated with shorter castration‐resistant prostate cancer–free survival, highlighting the ...
Fei Lin, Wen‐Cai Zheng, Yi‐Qiu Wang, Bin Lin, Yun‐Zhi Lin, Dong‐Ning Chen, Xiao‐Dong Li, Xue‐Yi Xue, Yong Wei, Ning Xu   +9 more
wiley   +1 more source

Analysis of venlafaxine by capillary zone electrophoresis

, 1997
Capillary electrophoresis has been used for the separation of venlafaxine and two of its impurities deriving from the synthesis process. The electrophoretic experiments were performed using background electrolytes at different pHs in the 2.5-9.2 range in
COTICHINI V, FANALI S, PORRA R
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Cross‐Organ Multi‐Omics Profiling of Systemic Alterations in 5xFAD Mice and Changes Associated with Huanglian Jiedu Decoction Treatment

Advanced Science, EarlyView.
Cross‐organ multi‐omics reveals coordinated inflammatory and metabolic disturbances in 5xFAD mice. Huanglian Jiedu Decoction improves cognition and alleviates brain and liver abnormalities. Complementary hepatocyte–microglia conditioned‐medium experiments suggest PPAR‐γ involvement in treatment‐associated changes in microglial inflammation, providing ...
Wenya Gao, Jing Gao, Xiaohui Su, Xiangying Kong, Xiaolu Wei, Tunan Ding, Tiantian Guo, Shuangrong Gao, Yanyan Zhou, Junyi Zhou, Haiyu Zhao   +10 more
wiley   +1 more source

Immunoaffinity Capillary Electrophoresis: Determination of Binding Constant and Stoichiometry for Antibody-Antigen Interaction

, 2009
Affinity capillary electrophoresis (ACE) can provide both qualitative and quantitative information on molecular interactions and affords the advantages of very low sample consumption, high mass sensitivity, short analysis time, and the use of automated ...
陳瑞堅;林世明, CHEN, RUEY-JIEN;LIN, SHI-MING   +1 more
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Topology‐Driven X‐Shaped DNA as a cGAS Stimulator to Promote Dendritic Cell Activation and Antitumor Vaccine Efficacy

Advanced Science, EarlyView.
X‐shaped DNA promotes multivalent cGAS assembly and enhances cGAS‐STING signaling. When conjugated with antigenic peptides, the resulting X‐DNA‐based peptide vaccine promotes dendritic cell activation, antigen presentation, and antitumor T‐cell responses.
Jiabei Li, Xuan Wang, Dali Wei, Zhejie Chen, Ziyi Wang, Qing Yu, Yu Yang, Shengpeng Wang   +7 more
wiley   +1 more source

Characterizing Biopolymer Electrolytes in Zinc–Air Batteries: Challenges, Best Practices, and a Robust Workflow Guiding Future Research Paths

Advanced Energy Materials, EarlyView.
Bio‐based gel polymer electrolytes promise sustainable, mechanically adaptable zinc–air batteries, yet their progress is constrained by inconsistent characterization. This review critically links formulation, structure, interfaces, and cell performance, identifies methodological gaps under alkaline operating conditions, and proposes application ...
Matteo Milanesi, Hiba Ali, Barbara Belza, Mattia F. Palermo, Claudio Gerbaldi, Giuseppe Antonio Elia, Nagore Ortiz‐Vitoriano   +6 more
wiley   +1 more source

Capillary electrophoresis: basic principles

, 2016
Capillary electrophoresis: basic ...
A Shallan (13571068), M Breadmore (13571071), Rosanne Guijt (13091724)   +2 more
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Prognostic Impact of FLT3‐ITD Allelic Ratio in AML Patients Treated With High‐Dose Anthracycline and a FLT3 Inhibitor

American Journal of Hematology, EarlyView.
ABSTRACT The prognostic value of FLT3 internal tandem duplication (FLT3‐ITD) in acute myeloid leukemia (AML) has traditionally been stratified according to the ITD/wild‐type allelic ratio (AR) and NPM1 co‐mutation status. We evaluated the prognostic impact of FLT3‐ITD AR in 459 newly diagnosed AML patients younger than 60 years enrolled in the ...
Mathieu Leclerc, Etienne Audureau, Nicolas Duployez, Mathilde Hunault, Emmanuelle Tavernier, Cécile Pautas, Sarah Bertoli, Emmanuel Raffoux, Marie‐Anne Hospital, Tony Marchand, Maël Heiblig, Sylvain Chantepie, Martin Carre, Pierre Peterlin, Maria‐Pilar Gallego‐Hernanz, Romain Guieze, Célestine Simand, Pascal Turlure, Anne Huynh, Emilie Lemasle, Ludovic Gabellier, Juliette Lambert, Felipe Suarez, Samy Chraibi, Laurence Sanhes, Karine Celli‐Lebras, Ariane Mineur, Claude Gardin, Jean‐Valère Malfuson, Thomas Cluzeau, Norbert Vey, Régis Peffault de Latour, Lucie Rigolot, Isabelle Luquet, Dominique Penther, Raphael Itzykson, Eric Delabesse, Jean‐François Hamel, Stéphane de Botton, Arnaud Pigneux, Hervé Dombret, Claude Preudhomme, Christian Recher, Pierre‐Yves Dumas   +43 more
wiley   +1 more source

Advanced Analytical Methods for Pharmaceutical and Diagnostic Applications

CHIMIA, 1997
Driving forces for the development of novel analytical technologies in the life-science industry are described. Technologies which either were developed in Bio-Analytical Research or brought to a reliability required for routine applications ...
Markus Ehrat, Gert L. Duveneck, Gerhard M. Kresbach, Peter Oroszlan, Aran Paulus   +4 more
doaj  

Repartition effect of aromatic polyaniline coatings on the separation of bioactive peptides in capillary electrophoresis

, 2002
The capillary walls of fused-silica capillary electrophoresis (CE) columns were modified with a thin film of polyaniline (PANI), providing open-tubular columns with a stable coating containing aromatic groups and amine functionalities. Fast and efficient
Turner, APF,, Piletsky, SA,, Bossi, A,, Righetti, PG,   +3 more
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